Feng-Yi Yang Distinguished Professor

Education
National Taiwan University, Taipei, Taiwan
Ph.D. in Biomedical Engineering
Research Interests
Medical Ultrasound, Medical Imaging Integrated application, Brain Science, Biomedical Engineering, Neuromodulation Translational Medicine

Medical Ultrasound Laboratory

Office : Experimental Building B322R  

Tel : +886-2-28267281

Lab Tel : +886-2-28267000 ext.65546/65522

E-mail : fyyang1@nycu.edu.tw

Office Hour : Wed. pm 13:30 ~ 15:30

新創獎官方網站技術介紹頁面，網址：https://reurl.cc/p6WMnd

Education

● 2004 – 2007 National Taiwan University, Taipei, Taiwan Ph.D. in Biomedical Engineering

● 1995 – 1997 National Yang-Ming University, Taipei, Taiwan M.S. in Biomedical Engineering

● 1989 – 1993 National Chiao Tung University, Hsinchu, Taiwan B.S. in Electrical Engineering

Work Experience

● 2021 – present National Yang Ming Chiao Tung University, Taipei, Taiwan

DistinguishedProfessor & Chairman,Department of Biomedical Imaging and Radiological Sciences

Director, Medical Ultrasound Lab

● 2019 – 2021 National Yang-Ming University, Taipei, Taiwan

DistinguishedProfessor,Department of Biomedical Imaging and Radiological Sciences

   Director, Medical Ultrasound Lab

● 2014 – 2019 National Yang-Ming University, Taipei, Taiwan

Professor,Department of Biomedical Imaging and Radiological Sciences

   Director, Medical Ultrasound Lab

● 2011 – 2014  National Yang-Ming University, Taipei, Taiwan

Associate Professor,Department of Biomedical Imaging and Radiological Sciences

    Director, Medical Ultrasound Lab

● 2008 – 2011  National Yang-Ming University, Taipei, Taiwan

Assistant Professor,Department of Biomedical Imaging and Radiological Sciences

   Director, Medical Ultrasound Lab

● 2007 BENQ Trident Medical Corporation, Taipei, Taiwan

Manager, Department of Research & Development

● 2003 – 2004  Ministry of Health and Welfare, Taipei, Taiwan

    Technician, Food and Drug Administration

● 1997 – 2003   Taiwan Semiconductor Manufacturing Company, Hsinchu, Taiwan

    Senior Engineer

Certificate

  • 2003 Civil Service Level 3 Senior Examination, Biomedical Engineering, Taiwan
  • 2008   Radiation Safety Certificate

Honors and Awards

2021 – 2023    Academic Achievement Award, National Yang Ming Chiao Tung University, Taiwan

2020            Excellent Paper Award, Veterans General Hospitals University System of Taiwan Joint Research Program, Taiwan

2019 – 2022    Distinguished Professor, National Yang Ming Chiao Tung University, Taiwan

2019 – 2021    Academic Achievement Award, National Yang-Ming University, Taiwan

2018            Future Tech Breakthrough Award, Ministry of Science and Technology, Taiwan

2018             Excellent Paper Award, Veterans General Hospitals University System of Taiwan Joint Research Program, Taiwan

2017 – 2019    Academic Achievement Award, National Yang-Ming University, Taiwan

2015 – 2017    Academic Achievement Award, National Yang-Ming University, Taiwan

2014            Excellent Paper Award, Veterans General Hospitals University System of Taiwan Joint Research Program, Taiwan

2013 – 2015    Academic Achievement Award, National Yang-Ming University, Taiwan              

2013          Academia Sinica Research Award for Junior Researcher, Academia Sinica of Taiwan

2013 – 2016    Excellent Young Investigator Grant, Ministry of Science and Technology, Taiwan

 2012           National Innovation Award, Institute for Biotechnology and Medicine Industry, Taiwan

 2011 – 2013  Academic Achievement Award, National Yang-Ming University, Taiwan

 2010 – 2011  Outstanding Paper Award, National Yang-Ming University, Taiwan

 2010             Excellent Investigator Grant, Ministry of Science and Technology, Taiwan

Biography

Feng-Yi Yang (楊逢羿) was born and grew up in Taipei, Taiwan. He received the B.S. degree in electrical engineering from National Chiao Tung University, Hsinchu, Taiwan, in 1993, and the M.S. and Ph.D. degrees from National Yang-Ming University and National Taiwan University, Taipei, Taiwan, in 1997, and 2007, respectively, all in biomedical engineering. Dr. Yang was an assistant professor since 2008 and is now a distinguished professor in the Department of Biomedical Imaging and Radiological Sciences, School of Biomedical Science and Engineering, National Yang-Ming University, Taipei, Taiwan. His research interests are primarily concerned with therapeutic ultrasound, ultrasound neuromodulation, ultrasound drug delivery, biomedical engineering, medical imaging, and medical physics. He received the Future Tech Breakthrough Award (2018) fromMinistry of Science and Technology, Academia Sinica Research Award (2013) for Junior Researchers from Academia Sinica of Taiwan, National Innovation Award (2012) from Institute for Biotechnology and Medicine Industry of Taiwan, Academic Achievement Award (2011-2020) from National Yang Ming University.

Research Grants

  1. Far Eastern Memorial Hospital-National Yang-Ming University Joint Research Program (112DN27), 2023, Project title: Evaluation of effects of ultrasound stimulation on dopamine in rat brain of schizophrenia model, Role: Principal Investigator
  2. National Science and Technology Council of Taiwan (NSTC 111-2218-E-A49-033-MY3), 2022-2025, Project title: Investigation of neuromodulation and mechanism of abdominal ultrasound stimulation on inflammatory bowel and brain disease through the gut-brain axis, Role: Principal Investigator
  3. National Science and Technology Council of Taiwan (NSTC111-2314-B-A49-045-MY3), 2022-2025, Project title: Effects and mechanisms of low-intensity ultrasound on the attenuation of inflammatory response in colon and brain by stimulated abdomen, Role: Principal Investigator
  4. Far Eastern Memorial Hospital-National Yang-Ming University Joint Research Program (111DN27), 2021, Project title: Study of ultrasound stimulation reverses the abnormality of protein expression in rat schizophrenia model, Role: Principal Investigator
  5. Cheng Hsin General Hospital Fundation (CY11113), 2021, Project title: Investigation of the effect of ultrasound on vascular permeability of stroke using dynamic contrast-enhanced MRI, Role: Principal Investigator
  6. Ministry of Science and Technology of Taiwan (MOST 110-2314-B-A49A-502-MY3), 2021-2024, Project title: Effects and mechanisms of ultrasound neuromodulation on the treatment of multiple sclerosis, Role: Principal Investigator
  7. Far Eastern Memorial Hospital-National Yang-Ming University Joint Research Program (110DN33), 2021, Project title: Investigation of effects of transcranial ultrasound stimulation on the treatment of schizophrenia, Role: Principal Investigator
  8. Cheng Hsin General Hospital Fundation (CY11006), 2021, Project title: A feasibility study of transcranial ultrasound stimulation on stroke patients, Role: Principal Investigator
  9. Ministry of Science and Technology of Taiwan (MOST 109-2321-B-010-004-), 2020, Project title: Feasibility study and system development of transcranial ultrasound stimulation on the treatment of Alzheimer’s disease II, Role: Principal Investigator
  10. Cheng Hsin General Hospital Fundation (CY10927), 2020, Project title: Investigation of the mechanisms of ultrasound improves brain injury and long-term outcomes, Role: Principal Investigator
  11. Ministry of Science and Technology of Taiwan (MOST 108-2314-B-010-034-MY3), 2019-2022, Project title: Effects and mechanisms of transcranial ultrasound stimulation on the treatment of Alzheimer’s disease, Role: Principal Investigator
  12. Ministry of Science and Technology of Taiwan (MOST 108-2321-B-010-005-), 2019, Project title: Feasibility study and system development of transcranial ultrasound stimulation on the treatment of Alzheimer’s disease I, Role: Principal Investigator
  13. Cheng Hsin General Hospital Fundation (CY10833), 2019, Project title: Study of ultrasound alleviates neuronal degeneration and apoptosis in brain injury, Role: Principal Investigator
  14. Veterans General Hospitals University System of Taiwan Joint Research Program (VGHUST107-G7-3-1), 2017, Project title: Evaluation of the Treatment of Low-Intensity Pulsed Ultrasound in an Animal Model of Traumatic Brain Injury, Role: Principal Investigator
  15. Cheng Hsin General Hospital Fundation (CY10721), 2018, Project title: Study of ultrasound promotes brain-derived neurotrophic factor and alleviates brain injury, Role: Principal Investigator
  16. Ministry of Science and Technology of Taiwan (MOST 106-2221-E-010-004-MY3), 2017-2020, Project title: Effects and mechanisms of low-intensity pulsed ultrasound on the treatment of schizophrenia, Role: Principal Investigator
  17. Ministry of Science and Technology of Taiwan (MOST 106-2314-B-002-018), 2017-2018, Project title: Effects and mechanisms of low-intensity pulsed ultrasound on the prevention of ischemic stroke and its recurrence, Role: Co-Principal Investigator
  18. Veterans General Hospitals University System of Taiwan Joint Research Program (VGHUST106-G7-6-1), 2017, Project title: The treatment efficacy of LPS-induced memory impairment in Alzheimer’s disease animal model by low intensity ultrasound, Role: Principal Investigator
  19. Cheng Hsin General Hospital Fundation (CY10622), 2017, Project title: Study of ultrasound modulates blood-brain barrier permeability and alleviates brain edema, Role: Principal Investigator
  20. Ministry of Science and Technology of Taiwan (MOST 105-2221-E-010-003), 2016-2017, Project title: Investigation of the Treatment of Low-Intensity Pulsed Ultrasound on Traumatic Brain Injury, Role: Principal Investigator
  21. Ministry of Science and Technology of Taiwan (MOST 105-2314-B-002-013), 2016-2017, Project title: Effects and mechanisms of low-intensity pulsed ultrasound on the prevention of ischemic stroke and its recurrence, Role: Co-Principal Investigator
  22. Ministry of Science and Technology of Taiwan (MOST 104), 2015-2016, Project title: Germination Program, Role: Principal Investigator
  23. Ministry of Science and Technology of Taiwan (MOST 104-2314-B-010-003-MY3), 2015-2018, Project title: Low intensity pulsed ultrasound stimulates neurotrophic factors in brain, Role: Principal Investigator
  24. Cheng Hsin General Hospital Fundation (CY10418), 2015, Project title: Low-Intensity Pulsed Ultrasound Enhance Neurotrophic Factors for Post Traumatic Stress Disorder, Role: Principal Investigator
  25. Veterans General Hospitals University System of Taiwan Joint Research Program (VGHUST104-G7-6-1), 2015, Project title: The treatment efficacy of post traumatic stress disorder by low intensity ultrasound, Role: Principal Investigator
  26. SPARK Taiwan Program, 2014-2016, Project title: Ultrasound Neuroprotective Treatment System, Role: Principal Investigator
  27. Cheng Hsin General Hospital Fundation (103F003C17), 2014, Project title: The neuromodulation on seizure control by low intensity focused ultrasound, Role: Principal Investigator
  28. Ministry of Science and Technology of Taiwan (MOST 102-2221-E-010-005-MY3), 2013-2016, Project title: Real-Time Evaluation of Pharmacokinetics of ultrasound-induced blood-brain barrier opening using dynamic contrast-enhanced MRI, Role: Principal Investigator
  29. Cheng Hsin General Hospital Fundation (102F218C11), 2013, Project title: Pharmacokinetic Evaluation of 111In-Labeled Targeted Drug in Brain Tumor after Blood-Brain Barrier Opening with Focused Ultrasound, Role: Principal Investigator
  30. Yen Tjing Ling Medical Foundation (CI-102-8), 2013, Project title: Evaluation of Permeability of ultrasound-induced blood-brain barrier disruption using dynamic contrast-enhanced MRI, Role: Principal Investigator
  31. Ministry of Science and Technology of Taiwan (MOST 101-2320-B-010-036-MY3), 2013-2016, Project title: Investigation of protein expression and pharmacokinetic analysis of the target region after transient blood-brain barrier disruption induced by focused ultrasound, Role: Principal Investigator
  32. Department of Health of Taiwan (DOH101-TD-PB-111-TM012), 2012, Project title: Local delivery of ultrasound and target drug is synergistic in the treatment of glioma, Role: Principal Investigator
  33. Cheng Hsin General Hospital Fundation (101F195CY18), 2012, Project title: Permeability Evaluation of Blood-Brain Barrier Disruption Induced with Focused Ultrasound by dynamic contrast-enhanced MRI, Role: Principal Investigator
  34. Ministry of Science and Technology of Taiwan (MOST 100-2321-B-010-010), 2011, Project title: Evaluation of Pharmacokinetics of 4-Borono-2-18F-Fluoro-L-Phenylalanine for Boron Neutron Capture Therapy in a Glioma-Bearing Rat Model with Ultrasound-Induced targeted Blood–Brain Barrier Disruption, Role: Principal Investigator
  35. Yen Tjing Ling Medical Foundation (CI-100-17), 2011, Project title: Quantitative evaluation of enhanced target drug delivery through blood-tumor barrier by focused ultrasound, Role: Principal Investigator
  36. Cheng Hsin General Hospital Fundation (100F117CY25), 2011, Project title: Quantitative Evaluation of Blood-Brain Barrier Disruption Induced with Focused Ultrasound by SPECT, Role: Principal Investigator
  37. Veterans General Hospitals University System of Taiwan Joint Research Program (VGHUST100-G1-3-3), 2011, Project title: Evaluation of therapeutic efficacy for target drug in brain tumor therapy with blood-brain barrier disruption induced by focused ultrasound, Role: Principal Investigator
  38. Ministry of Science and Technology of Taiwan (MOST 99-2321-B-010-017), 2010, Project title: Evaluation of Pharmacokinetics of 4-Borono-2-18F-Fluoro-L-Phenylalanine for Boron Neutron Capture Therapy in a Glioma-Bearing Rat Model with Ultrasound-Induced targeted Blood–Brain Barrier Disruption, Role: Principal Investigator
  39. Ministry of Science and Technology of Taiwan (MOST 99-2314-B-010-028), 2010, Project title: Evaluation of enhanced drug delivery and treatment efficacy through blood-tumor barrier by MR imaging-monitored focused ultrasound, Role: Principal Investigator
  40. Yen Tjing Ling Medical Foundation (CI-99-8), 2010, Project title: Quantitative evaluation of enhanced drug delivery through blood-tumor barrier by MR imaging-monitored focused ultrasound, Role: Principal Investigator
  41. Ministry of Science and Technology of Taiwan (MOST 99-NU-E-016-003-), 2010, Project title: Validity and Therapeutic Evaluation of Neuroreceptor imaging in ADHD, Role: Co-Principal Investigator
  42. Ministry of Science and Technology of Taiwan (MOST 98-2622-B-010-001-CC3), 2009, Project title: A development of blood pressure monitor for peak systolic velocity measurement, Role: Principal Investigator
  43. Ministry of Science and Technology of Taiwan (MOST 97-2320-B-010-004), 2008, Project title: Study of targeted drug delivery through blood-brain barrier by MR imaging-guided transcranial focused ultrasound, Role: Principal Investigator

Journal Publications

Google Scholar

https://reurl.cc/65E0M6

Journal papers (*corresponding author)

  1. Tsung-Yu Pan, Yi-Ju Pan, Shih-Jen Tsai, Che-Wen Tsai, Feng-Yi Yang*, ” Focused ultrasound stimulates the prefrontal cortex and prevents MK-801-induced psychiatric symptoms of schizophrenia in rats”, Schizophrenia Bulletin, published on line, 2023 (SCI, IF:7.348; Rank:24/143 in “Psychiatry”)
  2. Wei-Shen Su, Chun-Hu Wu, Wen-Shin Song, Szu-Fu Chen, Feng-Yi Yang*, ” Low-intensity Pulsed Ultrasound Ameliorates Glia-mediated Inflammation and Neuronal Damage in Experimental Intracerebral Hemorrhage Conditions”, Journal of Translational Medicine, revised, 2023 (SCI, IF:8.448; Rank:25/139 in “Medicine, Research & Experimental”)
  3. Feng-Yi Yang*, Wan-Hsuan Chan, Cong-Yong Gao, Yin-Ting Zheng, Chia-Hua Ke ” Transabdominal ultrasound alleviates LPS-induced neuroinflammation by modulation of TLR4/NF-kB signaling and tight junction protein expression”, Life Sciences, Vol. 325, 121769, 2023 (SCI, IF:6.780; Rank:36/279 in “Pharmacology & Pharmacy”)
  4. Chin-Hung Hsu, Yi-Ju Pan, Yin-Ting Zheng, Raymond Y. Lo, Feng-Yi Yang* ” Ultrasound reduces inflammation by modulating M1/M2 polarization of microglia through STAT1/STAT6/PPARg signaling pathways”, CNS Neuroscience & Therapeutics, accepted, 2023 (SCI, IF:7.035; Rank:31/279 in “Pharmacology & Pharmacy”)
  5. Wen-Shin Song, Tai-Ho Hung, Shing-Hwa Liu, Yin-Ting Zheng, Hsin-Mei Lin, Feng-Yi Yang*, ”Neuroprotection by abdominal ultrasound in lipopolysaccharide-induced systemic inflammation”, International Journal of Molecular Sciences, Vol. 24, No. 11, pp.9329, 2023 (SCI, IF:6.208; Rank:69/296 in “Biochemistry & molecular biology”)
  6. Li-Hsin Huang, Zih-Yun Pan, Yi-Ju Pan, Feng-Yi Yang*, ” Magnetization transfer ratio for assessing remyelination after transcranial ultrasound stimulation in the lysolecithin rat model for multiple sclerosis”, Cerebral Cortex, Vol. 33, No. 4, pp.1403-1411, 2023 (SCI, IF:5.357; Rank:68/273 in “Neurosciences”)
  7. Feng-Yi Yang*, Yin-Ting Zheng, “Ultrasound Alleviates Lipopolysaccharide-Induced Colonic Damage”, Proceedings of the 2023 International Conference of the IEEE Engineering in Medicine and Biology Society, accepted, Sydney, Australia, Jul. 24-27, 2023 (EI).
  8. Feng-Yi Yang*, Li-Hsin Huang, Meng-Ting Wu, Zih-Yun Pan, ” Ultrasound neuromodulaiton reduces demyelination in a rat model of multiple sclerosis”, International Journal of Molecular Sciences, Vol. 23, No. 17, pp.10034, 2022 (SCI, IF:6.208; Rank:69/296 in “Biochemistry & molecular biology”)
  9. Che-Wen Tsai, Shih-Jen Tsai, Yi-Ju Pan, Hsin-Mei Lin, Tsung-Yu Pan, Feng-Yi Yang*, ”Transcranial ultrasound stimulation reverses behavior changes and the expression of calcium-binding protein in a rodent model of schizophrenia”, Neurotherapeutics, accepted, 2021 (SCI, IF:7.620; Rank:17/276 in “Pharmacology & pharmacy”)
  10. Wen-Shin Song, Chen-Yu Sung, Chia-Hua Ke, Feng-Yi Yang*, ”Anti-inflammatory and neuroprotective effects of transcranial ultrasound stimulation on Parkinson’s disease”, Ultrasound in Medicine and Biology, Vol. 48, No. 2, pp.265-274, 2022 (SCI, IF: 2.998; Rank:7/31 in “Acoustics”)
  11. Pai-Kai Chiang, Wei-Kung Tsai, Wen-Hsiang Allen Chiu, Jhen-Bin Lin,Feng-Yi Yang*, Jie Lee”Muscle loss during androgen deprivation therapy is associated with higher risk of non-cancer mortality in high-risk prostate cancer”, Frontiers in Oncology, published on line, 2021 (SCI, IF:6.244; Rank:62/242in “Oncology”)
  12. Chen-Yu Sung, Pai-Kai Chiang, Che-Wen Tsai, Feng-Yi Yang*, ”Low-intensity pulsed ultrasound enhances neurotrophic factors and alleviates neuroinflammation in a rat model of Parkinson’s disease”, Cerebral Cortex, Vol. 32, No. 1, pp.176-185, 2022 (SCI, IF:5.357; Rank:68/273in “Neurosciences”)
  13. Tai-Ho Hung, Yu-Cheng Liu, Chun-Hu Wu, Chien-Cheng Chen, Hsien Chao, Feng-Yi Yang*, Szu-Fu Chen, ”Antenatal low-intensity pulsed ultrasound reduces neurobehavioral deficits and brain injury following dexamethasone-induced intrauterine growth restriction”, Brain Pathology, Vol. 31, No. 6, e12968, 2021 (SCI, IF:6.508; Rank:8/77in “Pathology”)
  14. Jia-Wei Chang, Meng-Ting Wu, Wen-Shin Song, Feng-Yi Yang*, ” Ultrasound stimulation suppresses LPS-induced proinflammatory responses by regulating NF-kB and CREB activation in microglial cells”, Cerebral Cortex, Vol. 30, No. 8, pp.4597-4606, 2020 (SCI, IF:6.559; Rank:16/252 in “Neurosciences”)
  15. Tao-Tao Chen, Tsuo-Hung Lan, Feng-Yi Yang*, ” Low-intensity pulsed ultrasound attenuates LPS-induced neuroinflammation and memory impairment by modulation of TLR4/ NF-kB signaling and CREB/BDNF expression”, Cerebral Cortex, Vol. 29, No. 4, pp.1430-1438, 2019 (SCI, IF:6.559; Rank:16/252 in “Neurosciences”)
  16. Pai-Kai Chiang, Feng-Yi Yang*, ” A Potential Treatment of Low Intensity Pulsed Ultrasound on Cavernous Nerve Injury for Erectile Dysfunction”, Medical Hypotheses, Vol. 122, pp.19-21, 2019 (SCI, IF:1.12; Rank:25/259 in “Neurosciences”)
  17. Chang-Mu Chen, Cheng-Tien Wu, Ting-Hua Yang, Shing-Hwa, Liu, Feng-Yi Yang*, ” Preventive Effect of Low Intensity Pulsed Ultrasound against Experimental Cerebral Ischemia/Reperfusion Injury via Apoptosis Reduction and Brain-derived Neurotrophic Factor Induction”, Scientific Reports, Vol. 8: 5568, 2018 (SCI, IF:4.259; Rank:10/64 in “Multidisciplinary sciences”)
  18. Szu-Fu Chen, Wei-Shen Su, Chun-Hu Wu, Tsuo-Hung Lan, Feng-Yi Yang*, ” Transcranial Ultrasound Stimulation Improves Long-term Functional Outcomes and Protects Against Brain Damage in Traumatic Brain Injury”, Molecular Neurobiology, Vol. 55, No. 8, pp.7079-7089, 2018 (SCI, IF:6.190; Rank:25/259 in “Neurosciences”)
  19. Yi-Li Lin, Meng-Ting Wu, Feng-Yi Yang*, ” Pharmacokinetics of Doxorubicin in Glioblastoma Multiforme following Ultrasound-Induced Blood-Brain Barrier Disruption as Determined by Microdialysis”, Journal of Pharmaceutical and Biomedical Analysis, Vol. 149, pp.482-487, 2018 (SCI, IF:3.255; Rank:18/76 in “Chemistry”)
  20. Wei-Shen Su, Chun-Hu Wu, Szu-Fu Chen, Feng-Yi Yang*, ” Transcranial Ultrasound Stimulation Promotes Brain-derived Neurotrophic Factor and Reduces Apoptosis in a Mouse Model of Traumatic Brain Injury”, Brain Stimulation, Vol. 10, No. 6, pp.1032-1041, 2017 (SCI, IF:6.078; Rank:16/194 in “Clinical Neurology”)
  21. Wei-Shen Su, Chun-Hu Wu, Szu-Fu Chen, Feng-Yi Yang*, ” Low-intensity pulsed ultrasound improves behavioral and histological outcomes after experimental traumatic brain injury”, Scientific Reports, Vol. 7: 15524, 2017 (SCI, IF:4.259; Rank:10/64 in “Multidisciplinary sciences”)
  22. Shing-Hwa Liu, Yi-Long Lai, Bo-Lin Chen, Feng-Yi Yang*, ”Ultrasound enhances the expression of brain-derived neurotrophic factor in astrocyte through activation of TrkB-Akt and Calcium-CaMK signaling pathways”, Cerebral Cortex, Vol. 27, No. 6, pp.3152-3160, 2017 (SCI, IF:8.665; Rank:16/252 in “Neurosciences”)
  23. Sin-Luo Huang, Chi-Wei Chang, Yi-Hsuan Lee, Feng-Yi Yang*, ” Protective effect of low-intensity pulsed ultrasound on memory impairment and brain damage in rats with vascular dementia”, Radiology, Vol. 282, No. 1, pp.113-122, 2017 (SCI, IF:6.867; Rank:2/125 in “Radiology”)
  24. Feng-Yi Yang*, Sheng-Fang Huang, Irene Han-Juo Cheng, ”Behavioral Alterations Following Blood-Brain Barrier Disruption Stimulated by Focused Ultrasound”, Oncotarget, Vol. 7, No. 19, pp.27916-27925, 2016 (SCI, IF:6.359; Rank:20/211 in “Oncology”)
  25. Wei-Shen Su, Min-Lan Tsai, Sin-Luo Huang, Shing-Hwa Liu, Feng-Yi Yang*, ”Controllable Permeability of Blood-Brain Barrier and Reduced Brain Injury through Low-Intensity Pulsed Ultrasound Stimulation”, Oncotarget, Vol. 6, No. 39, pp.42290-42299, 2015 (SCI, IF:6.359; Rank:20/211 in “Oncology”)
  26. Feng-Yi Yang*, Wen-Yuan Chang, Wei-Ting Lin, Jeng-Jong Hwang, Yi-Chun Chien, Hsin-Ell Wang, Min-Lan Tsai, ”Focused Ultrasound Enhanced Molecular Imaging and Gene Therapy for Multifusion Reporter Gene in Glioma-Bearing Rat Model”, Oncotarget, Vol. 6, No. 34, pp.36260-36268, 2015 (SCI, IF:6.359; Rank:20/211 in “Oncology”)
  27. Wei-Ting Lin, Ran-Chou Chen, Wen-Wei Lu, Shing-Hwa Liu, Feng-Yi Yang*, ” Protective effects of low-intensity pulsed ultrasound on aluminum-induced cerebral damage in Alzheimer’s disease rat model”, Scientific Reports, Vol. 5: 9671, 2015 (SCI, IF:5.078; Rank:5/55 in “Multidisciplinary sciences”)
  28. Feng-Yi Yang*, Wen-Wei Lu, Wei-Ting Lin, Chi-Wei Chang, Sin-Luo Huang, ” Enhancement of Neurotrophic Factors in Astrocyte for Neuroprotective Effects in Brain Disorders Using Low-Intensity Pulsed Ultrasound Stimulation”, Brain Stimulation, Vol. 8, No. 3, pp.465-473, 2015 (SCI, IF:5.432; Rank:36/251 in “Neurosciences”)
  29. Feng-Yi Yang*, Wen-Yuan Chang, Jyh-Cheng Chen, Lin-Chien Lee, Yi-Shun Hung, ”Quantitative Assessment of Cerebral Glucose Metabolic Rates after Blood-Brain Barrier Disruption Induced by Focused Ultrasound Using FDG-MicroPET”, NeuroImage, Vol. 90, pp.93-98, 2014 (SCI, IF:6.252; Rank:3/120 in “Radiology”)
  30. Feng-Yi Yang*, Wen-Yuan Chang, Jia-Je Li, Hsin-Ell Wang, Jyh-Cheng Chen, Chi-Wei Chang, ”Pharmacokinetic Analysis and Uptake of 18F-FBPA-Fr Following Ultrasound Induced Blood-Brain Barrier Disruption for Potential Use to Enhance Boron Delivery for Neutron Capture Therapy”, Journal of Nuclear Medicine, Vol. 55, No. 4, pp.616-621, 2014 (SCI, IF:5.774; Rank:6/120 in “Radiology”)
  31. Ying-Ling Chen**, Chung-Yih Wang**, Feng-Yi Yang**, Bo-Sheng Wang**, Jason Y. Chen, Liang-Ting Lin, Jyh-Der Leu, Fu-Du Chen, Yi-Jang Lee, Wei Chen, ”Synergistic effects of glycated chitosan with high-intensity focused ultrasound on suppression of metastases in a syngeneic breast tumor model”, Cell Death and Disease, Vol. 5, e1178, 2014 (**Equal first author; SCI, IF:6.044; Rank:35/185 in “Cell Biology”)
  32. Sheng-Yao Huang, Chia-En Ko, Gin-Shin Chen, I-Fang Chung, Feng-Yi Yang*, ” Focused Ultrasound Simultaneous Irradiation/MRI Imaging, and Two-stage General Kinetic Model”, PLOS ONE, Vol. 9, Issue 6, e100280, 2014 (SCI, IF:3.730; Rank:7/56 in “Multidisciplinary sciences”)
  33. Feng-Yi Yang*, Yi-Li Lin, Fong-In Chou, Yu-Chuan Lin, Yen-Wan Hsueh Liu, Lun-Wei Chang, Yu-Ling Hsieh, ” Pharmacokinetics of BPA in Gliomas with Ultrasound Induced Blood-Brain Barrier Disruption as Measured by Microdialysis”, PLOS ONE, Vol. 9, Issue 6, e100104, 2014 (SCI, IF:3.730; Rank:7/56 in “Multidisciplinary sciences”)
  34. Feng-Yi Yang*, Chia-En Ko, Sheng-Yao Huang, I-Fang Chung, Gin-Shin Chen, ” Pharmacokinetic Changes Induced by Focused Ultrasound in Glioma-Bearing Rats as Measured by Dynamic Contrast-Enhanced MRI”, PLOS ONE, Vol. 9, Issue 3, e92910, 2014 (SCI, IF:3.730; Rank:7/56 in “Multidisciplinary sciences”)
  35. Chun-Yi Wu, Pei-Chia Chan, Lin-Shan Chou, Chi-Wei Chang, Feng-Yi Yang, Ren-Shyan Liu, Shih-Hwa Chiou, Yi-Wei Chen, Sang-Hue Yen, Hsin-Ell Wang, ” Pulsed focused ultrasound enhances boron drug accumulation in a human head and neck cancer xenograft-bearing mouse model”, Molecular Imaging & Biology, Vol.16, Issue 1, pp.95-101, 2014 (SCI, IF:3.095; Rank:25/120 in “Radiology”)
  36. Feng-Yi Yang*, Wei-Hsiu Chiu, ”Focused Ultrasound-Modulated Glomerular Ultrafiltration Assessed by Functional Changes in Renal Arteries”, PLOS ONE, Vol. 8, Issue 1, e54034, 2013 (SCI, IF:4.092; Rank:12/84 in “Multidisciplinary sciences”)
  37. Feng-Yi Yang*, Chien-Cheng Chen, Yi-Hsuan Kao, Chuan-Lin Chen, Chia-En Ko, Shih-Cheng Horng, Ran-Chou Chen, ”Evaluation of Dose Distribution of Molecular Delivery after Blood-Brain Barrier Disruption by Focused Ultrasound with Treatment Planning”, Ultrasound in Medicine and Biology, Vol. 39, No. 4, pp. 620-627, 2013 (SCI, IF: 2.493; Rank:4/29 in “Acoustics”)
  38. Tse-Ying Liu, Meng-Yu Wu, Meng-Hsuan Lin, Feng-Yi Yang, ”A novel ultrasound-triggered drug vehicle with multimodal imaging functionality”, Acta Biomaterialia, Vol. 9, Issue 3, pp.5453-5463, 2013 (SCI, IF: 4.865; Rank:3/72 in “Engineering, Biomedical”)
  39. Feng-Yi Yang*, Hsin-Ell Wang, Ren-Shyan Liu, Ming-Che Teng, Jia-Je Li, Maggie Lu, Ming-Cheng Wei, Tai-Tong Wong, ”Pharmacokinetic Analysis of 111In-Labeled Liposomal Doxorubicin in Murine Glioblastoma with Blood-Brain Barrier Disruption Induced by Focused Ultrasound”, PLOS ONE, Vol. 7, Issue 9, e45468, 2012 (SCI, IF:4.092; Rank:12/84 in “Multidisciplinary sciences”)
  40. Feng-Yi Yang*, Yi-Wei Chen, Fong-In Chou, Sang-Hue Yen, Yi-Li Lin, Tai-Tong Wong, ”Boron Neutron Capture Therapy for Glioblastoma Multiforme: Enhanced Drug Delivery and Antitumor Effect Following Blood-Brain Barrier Disruption Induced by Focused Ultrasound”, Future Oncology, Vol. 8, Issue 10, pp.1361-1369, 2012 (SCI, IF:3.163; Rank:74/194 in “Oncology”)
  41. Feng-Yi Yang*, Tai-Tong Wong, Ming-Che Teng, Ren-Shyan Liu, Maggie Lu, Hsiang-Fa Liang, Ming-Cheng Wei, ”Focused Ultrasound and Interleukin-4 Receptor-Targeted Liposomal Doxorubicin for Enhanced Targeted Drug Delivery and Antitumor Effect in Glioblastoma Multiforme”, Journal of Controlled Release, Vol. 160, Issue 3, pp.652-658, 2012 (SCI, IF:7.164; Rank:10/249 in “Pharmacology & Pharmacy”)
  42. Feng-Yi Yang*, Pei-Yi Lee, ”Efficiency of Drug Delivery Enhanced by Acoustic Pressure During Blood-Brain Barrier Disruption Induced by Focused Ultrasound”, International Journal of Nanomedicine, Vol. 7, pp.2573-2583, 2012 (SCI, IF:4.976; Rank:18/249 in “Pharmacology & Pharmacy”)
  43. Feng-Yi Yang*, Ming-Che Teng, Maggie Lu, Hsiang-Fa Liang, Yan-Ru Lee, Chueh-Chuan Yen, Muh-Lii Liang, Tai-Tong Wong, ”Treating Glioblastoma Multiforme with Selective High-Dose Targeted Liposomal Doxorubicin Chemotherapy Induced by Repeated Focused Ultrasound”, International Journal of Nanomedicine, Vol. 7, pp.965-974, 2012 (SCI, IF:4.976; Rank:18/249 in “Pharmacology & Pharmacy”)
  44. Feng-Yi Yang*, Hsin-Ell Wang, Guan-Liang Lin, Hui-Hsien Lin, Tai-Tong Wong, ”Evaluation of the Increase in Permeability of the Blood-Brain Barrier during Tumor Progression after Pulsed Focused Ultrasound”, International Journal of Nanomedicine, Vol. 7, pp.723-730, 2012 (SCI, IF:4.976; Rank:18/249 in “Pharmacology & Pharmacy”)
  45. Feng-Yi Yang*, Guan-Liang Lin, Shih-Cheng Horng, Ran-Chou Chen, “Prenatal Exposure to Diagnostic Ultrasound Impacts Blood-Brain Barrier Permeability in Rats” Ultrasound in Medicine and Biology, Vol. 38, No. 6, pp.1051-1057, 2012 (SCI, IF: 2.493; Rank:4/29 in “Acoustics”)
  46. Shih-Cheng Horng, Feng-Yi Yang, Shieh-Shing Lin, “Apply PSO and OCBA to Minimize the Overkills and Re-probes in Wafer Probe Testing”, IEEE Transactions on Semiconductor Manufacturing, Vol. 25, No. 3, pp. 531-540, 2012 (SCI, IF:0.722; Rank:159/244 in “Engineering, Manufacturing”)
  47. Shih-Cheng Horng, Feng-Yi Yang, “Simulation-Based Meta-heuristic Approach for Booking Limits Problem at a Hotel Baby”, Proceedings of the 2012 International Conference on Information Security and Intelligent Control, pp. 153-156, 2012 (EI)
  48. Shih-Cheng Horng, Feng-Yi Yang, “Ordinal Optimization Based Algorithm for Hotel Booking Limits Problem”, Proceedings of the International Symposium on Computer, Consumer and Control 2012, pp. 759-762, 2012 (EI)
  49. Shih-Cheng Horng, Feng-Yi Yang*, Shieh-Shing Lin, ” Embedding Evolutionary Strategy in Ordinal Optimization for Hard Optimization Problems,” Applied Mathematical Modelling, Vol. 36, pp.3753-3763, 2012 (SCI, IF:1.371; Rank:16/87 in “Engineering, Multidisciplinary”)
  50. Shih-Cheng Horng, Shieh-Shing Lin, Feng-Yi Yang*, ” Evolutionary Algorithm for Stochastic Job Shop Scheduling with Random Processing Time,” Expert Systems With Applications, Vol. 39, pp.3603-3610, 2012 (SCI, IF:1.924; Rank:48/247 in “Engineering, Electrical & Electronic”)
  51. Shih-Cheng Horng, Feng-Yi Yang, “Optimal Base‐stock Policy of the Assemble to Order Systems”, Proceedings of the 17th International Symposium on Artificial Life and Robotics, pp. 816-819, 2012 (EI)
  52. Feng-Yi Yang*, Chien-Cheng Chen, Shih-Cheng Horng, Wei-Hsiu Chiu, Chi-Fang Yeh, ”Microbubble-enhanced functional changes in arteries induced by pulsed high-intensity focused ultrasound exposure,” Medical Engineering & Physics, 34(3), pp.313-317, 2012 (SCI, IF:1.906; Rank:28/69 in “Engineering, Biomedical”)
  53. Feng-Yi Yang*, Shih-Cheng Horng, “Ultrasound Enhanced Delivery of Macromolecular Agents in Brain Tumor Rat Model”, Conference Proceedings IEEE Engineering in Medicine and Biology Society, pp. 5573-5576, 2011 (EI)
  54. Feng-Yi Yang*, Hsin-Ell Wang, Guan-Liang Lin, Ming-Che Teng, Hui-Hsien Lin, Tai-Tong Wong, Ren-Shyan Liu, ”Micro-SPECT/CT-Based Pharmacokinetic Analysis of 99mTc-DTPA in Rats with Blood-Brain Barrier Disruption Induced by Focused Ultrasound,” Journal of Nuclear Medicine, Vol. 52, No. 3, pp.478-484, 2011 (SCI, IF:7.022; Rank:1/111 in “Radiology”)
  55. Feng-Yi Yang, Guan-Liang Lin, Shih-Cheng Horng, Tien-Kuei Chang, Shih-Yen Wu, Tai-Tong Wong, Hsin-Ell Wang, ” Pulsed High-Intensity Focused Ultrasound Enhances the Relative Permeability of the Blood-Tumor Barrier in a Glioma-Bearing Rat Model,” IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 58, No. 5, pp.964-970, 2011 (SCI, IF:1.460; Rank:9/29 in “Acoustics”)
  56. Wei-Hsiu Chiu, Tao-Hsin Tung, Pei-Hsuan Yu, Kuang-Shing Shey, Shih-Cheng Horng, Feng-Yi Yang*, “Normative curves of fetal limb bones length for the ethnic Chinese population,” Ultrasound in Obstetrics and Gynecology, accepted,  2011 (SCI, IF: 3.163; Rank:3/29 in “Acoustics”)
  57. Feng-Yi Yang*, Yu-Shi Lin, Kai-Hsiang Kang and Tai-Kuang Chao, ”Reversible blood-brain barrier disruption by repeated transcranial focused ultrasound allows enhanced extravasation,” Journal of Controlled Release, 150(1) 111-116, 2011 (SCI, IF:7.164; Rank:10/249 in “Pharmacology & Pharmacy”)
  58. Shih-Cheng Horng, Feng-Yi Yang and Shieh-Shing Lin, ”Hierarchical Fuzzy Clustering Decision Tree for Classifying Recipes of Ion Implanter,” Expert Systems With Applications, Vol. 38, No. 1, pp.933-940, 2011 (SCI, IF:1.924; Rank:48/247 in “Engineering, Electrical & Electronic”)
  59. Shih-Cheng Horng, Feng-Yi Yang, “Combining Particle Swarm with Ordinal Optimization for Stochastic Simulation Optimization Problems”, Proceedings of the 8th Asian Control Conference, pp. 982-987, Kaohsiung, Taiwan, May 15-18 2011 (EI)
  60. Shih-Cheng Horng, Feng-Yi Yang, “Apply Particle Swarm Optimization to Maximize the Service Reliability of Grid Computing System”, Proceedings of the 25th International Conference on Information Networking,  pp. 235-240,  Kuala Lumpur, Malaysia, Jan. 26-28 2011 (EI)
  61. Feng-Yi Yang*, Shih-Cheng Horng, Yu-Shi Lin and Yi-Hsuan Kao, ”Association between contrast-enhanced MR images and blood-brain barrier disruption following transcranial focused ultrasound”, Journal of Magnetic Resonance Imaging, 2010; 32(3) 593-599 (SCI, IF:2.747; Rank:37/111 in “Radiology”)
  62. Wei-Hsiu Chiu, Tao-Hsin Tung, Ya-Shan Chen, Wei-Hsiung Wang, Shy-Mung Lee, Shih-Cheng Horng, Feng-Yi Yang*, “Normative curves of fetal nasal bone length for the ethnic Chinese population”, Irish Journal of Medical Science, Vol. 180, Number 1, pp.73-77, 2011 (SCI, IF: 0.661; Rank:95/151 in “Medicine”)
  63. Feng-Yi Yang*, Shih-Cheng Horng and Wei-Hsiu Chiu, ”Real-time ultrasound image-monitored focal changes of the vascular function in rats by pulsed HIFU”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 57, No. 7, pp.1594-1599, 2010 (SCI, IF:1.460; Rank:9/29 in “Acoustics”)
  64. Jun-Cheng Weng, Sheng-Kai Wu, Feng-Yi Yang, Win-Li Lin and Wen-Yih Tseng, “Pulse Sequence and timing of contrast-enhanced MRI for assessing blood-brain barrier disruption after transcranial focused ultrasound in the presence of hemorrhage”, Journal of Magnetic Resonance Imaging, 2010; 31(6) 1323-1330 (SCI, IF:2.747; Rank:37/111 in “Radiology”)
  65. Feng-Yi Yang*, Wei-Hsiu Chiu, Chi-Fang Yeh, “Color doppler sonographic evaluation of peak systolic velocity and pulsatility index in artery after pulsed HIFU exposure”, American Institute of Physics (AIP) conference proceedings,  2010 (EI)
  66. Feng-Yi Yang*, Wei-Hsiu Chiu, Shing-Hwa Liu and Feng-Ming Ho, “The length ratios between fetal limb bones and nasal bone in the general population”, European Journal of Obstetrics & Gynecology and Reproductive Biology, Vol. 148, No. 1, pp.99-100, 2010 (SCI, IF: 1.764; Rank:35/75 in “Obstetrics & Gynecology”)
  67. Feng-Yi Yang*, Wei-Hsiu Chiu, Shing-Hwa Liu, Guan-Liang Lin, and Feng-Ming Ho, ”Functional Changes in Arteries Induced by Pulsed High-Intensity Focused Ultrasound”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 56, No. 12, pp.2643-2649, 2009 (SCI, IF:1.460; Rank:9/29 in “Acoustics”)
  68. Feng-Yi Yang*, Shing-Hwa Liu, Feng-Ming Ho, Chi-Hong Chang, “Effect of ultrasound contrast agent dose on the duration of focused-ultrasound-induced blood-brain barrier disruption”, The Journal of the Acoustical Society of America, Vol. 126, No. 6, pp.3344-3349, 2009 (SCI, IF: 1.644; Rank:6/29 in “Acoustics”)
  69. Feng-Yi Yang, Wen-Mei Fu, Wen-Shiang Chen, Wei-Lan Yeh and Win-Li Lin, “Quantitative evaluation of the use of microbubbles with transcranial focused ultrasound on blood-brain barrier disruption”, Ultrasonics Sonochemistry, Vol. 15, No. 4, pp.636-643, 2008 (SCI, IF: 3.199; Rank:2/29 in “Acoustics”)
  70. Feng-Yi Yang, Wen-Mei Fu, Rong-Sen Yang, Houng-Chi Liou, Kai-Hsiang Kang and Win-Li Lin, “Quantitative evaluation of focused ultrasound with a contrast agent on blood-brain barrier disruption”, Ultrasound in Medicine and Biology, Vol. 33, No. 9, pp.1421-1427, 2007 (SCI, IF: 2.493; Rank:4/29 in “Acoustics”)
  71. Feng-Yi Yang, Tzu-Jung Mao, Yung-Yaw Chen, Hsu Chang, Win-Li Lin, “Beam steering and focusing ability of a contact ultrasound transducer for transskull brain disease therapy”, Biomedical Engineering – Applications, Basis, and Communications, Vol. 18, No. 6, pp.328-336, 2006 (SCI)
  72. F.Y. Yang, W.M. Fu, H.C. Liou, W.S. Chen, W.L. Lin, “In-vivo Investigation of the Effects of Ultrasound Contrast Agent and Focused Ultrasound on Blood-Brain Barrier Disruption”, IEEE Ultrasonics Symposium, pp.1592-1595, 2006 (EI)
  73. S.C. Horng, S.Y. Lin, M.H. Cheng, F.Y. Yang, C.H. Liu, W.Y. Lee, C.H. Tsai, “Reducing the Overkills and Retests in Wafer Testing Process”, IEEEI/SEMI Advanced Semiconductor Manufacturing Conference and Workshop, pp.286-291, 2003 (EI)

Conference papers (*corresponding author)

  1. Feng-Yi Yang*, Yin-Ting Zheng, “Ultrasound Alleviates Lipopolysaccharide-Induced Colonic Damage”, Proceedings ofthe 2023 International Conference of the IEEE Engineering in Medicine and Biology Society, accepted, Sydney, Australia, Jul. 24-27, 2023 (EI).
  2. Feng-Yi Yang*, Jia-Wei Chang, Cong-Yong Gao, “Ultrasound Alleviates LPS-induced Inflammation in Microglia”, 8th International Conference on Advanced Technology Innovation, Okinawa, Japan, April 01-05, 2023.
  3. Wei-Shen Su, Chun-Hu Wu, Feng-Yi Yang*, “Investigation of the transcranial ultrasound stimulation on neuron deficits in intracerebral hemorrhage animal model”, 5th Global Conference on Biomedical Engineering, Taipei, Taiwan, December 15-17, 2022.
  4. Zih-Yun Pan, Li-Hsin Huang, Feng-Yi Yang*, “Low-intensity pulsed ultrasound stimulation enhances remyelination in lysolecithin-induced model of multiple sclerosis”, 5th Global Conference on Biomedical Engineering, Taipei, Taiwan, December 15-17, 2022. (Best student award)
  5. Nai-Jie Hsiaw, Chun-Yen Lee, Szu-Fu Chen, Feng-Yi Yang*, “Low-intensity pulsed ultrasound improved cognitive function after experimental traumatic brain injury: Reducing the activation of astrocyte and microglia”, 14th International Congress of Cell Biology & 9th Asian Pacific Organization for Cell Biology, Taipei, Taiwan, November 7-11, 2022.
  6. Zih-Yun Pan, Li-Hsin Huang, Feng-Yi Yang*, “Monitoring remyelination by MRI after transcranial ultrasound stimulation in the rat brain”, 4th Asian Society of Magnetic Resonance in Medicine, Taipei, Taiwan, May 21-22, 2022.
  7. Feng-Yi Yang*, Tao-Tao Chen, “Ultrasound Protects against Ab-Mediated Cell Death”, International Conference on Advanced Technology Innovation, Sapporo, Hokkaido, Japan, July 15-18, 2019.
  8. Feng-Yi Yang*, Tao-Tao Chen, “Transcranial Ultrasound Improves Behavioral Performance via Anti-Neuroinflammation”, Proceedings of the 2018 International Conference of the IEEE Engineering in Medicine and Biology Society, pp.5573-5576, Hawaii, USA, Jul. 17-21, 2018 (EI).
  9. Wei-Shen Su, Chun-Hu Wu, Szu-Fu Chen, Feng-Yi Yang*, “Effect of Ultrasound Treatment in Traumatic Brain Injury Mice”, Neuroscience 2017, Washington, DC, USA, November 11-15, 2017.
  10. Wei-Shen Su, Feng-Yi Yang*, “Ultrasound Attenuates Blood-Brain Barrier Disruption and Cerebral Edema after Traumatic Brain Injury in Mice”,  International Journal of Psychiatry and Psychotherapy, 2, 54-57; 5th International Conference on Neurology, Agia Pelagia Beach, Heraklion, Crete, Greece, July 14-17, 2017.
  11. Wei-Shen Su, Feng-Yi Yang*, “Protective Effect of Ultrasound on Brain Injury in Mice”, International Society for Therapeutic Ultrasound (ISTU), Nanjing, China, May 31-June 2, 2017.
  12. Wei-Shen Su, Feng-Yi Yang*, “Controllable Permeability of Blood-Brain Barrier and Reduced Brain Injury through Low-Intensity Pulsed Ultrasound Stimulation”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2016.
  13. Feng-Yi Yang*, Sheng-Fang Huang, “Behavioural Assessment of Blood-Brain Barrier Opening Induced by Various Ultrasound Parameters”, International Conference on Advanced Technology Innovation, Bali, Indonesia, June 30-July 3, 2016.
  14. Feng-Yi Yang*, Sin-Luo Huang, “Protective Effect of Ultrasound on Brain Damage in Rats with Chronic Cerebral Hypoperfusion”, International Society for Therapeutic Ultrasound (ISTU), Tel Aviv, Israel, March 14-16, 2016.
  15. Yi-Li Lin, Chia-En Ko, Sheng-Yao Huang, I-Fang Chung, Feng-Yi Yang*,  “Duration and leakage of focused-ultrasound induced blood-brain barrier opening in rats measuring by dynamic contrast-enhanced MRI”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2015.
  16. Feng-Yi Yang*, Wen-Yuan Chang, Wei-Ting Lin, Jeng-Jong Hwang,  “Enhancement of gene delivery using focused ultrasound on brain tumor”, 2015 Annual Main Meeting of the Society of Experimental Biology,  Prague, Czech Republic, June 29-July 3, 2015.
  17. Feng-Yi Yang*, “Ultrasound Target Drug Delivery”, 7th Asian Oncology Summit, Shanghai, China, Apr. 10-12, 2015.
  18. Sin-Luo Huang, Chia-En Ko, Feng-Yi Yang*, “Pharmacokinetic Changes Induced by Focused Ultrasound in Brain Tumor as Assessed by Dynamic Contrast-Enhanced MRI”, 9th International Symposium of Medical Imaging and Radiological Sciences, ROC, 2014.
  19. Shih-Cheng Horng, Feng-Yi Yang, “Optimization of broadband wireless networks with centralized control using memetic algorithm”, Proceedings of the 28th International Conference on Information Networking,  Phuket, Thailand, Feb. 10-12, 2014.
  20. Yi-Li Lin, Wen-Yuan Chang, Hsin-Ell Wang, Jyh-Cheng Chen, Feng-Yi Yang*, “Pharmacokinetics of 18F-FBPA-Fr with Focused Ultrasound-Induced BBB-Disruption from micro-PET Imaging”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2013.
  21. Sheng-Yao Huang, Yi-Cheng Chen, Feng-Yi Yang, I-Fang Chung, Chun-Hung Su, “Finding Marker Genes from High Dimensional Expression Profiles: Divide-and-conquer Exploiting a Fuzzy Rule Based Framework”, Proceedings of the 2013 International Conference on Fuzzy Systems, pp.1-6, Hyderabad, India, Jul. 7-10, 2013 (EI)
  22. Feng-Yi Yang*, Shih-Cheng Horng, “Chemotherapy of Glioblastoma by Targeted Liposomal Platinum Compounds with Focused Ultrasound”, Proceedings of the 2013 International Conference of the IEEE Engineering in Medicine and Biology Society, pp.5573-5576, Osaka, Japan, Jul. 3-7, 2013 (EI)
  23. Shih-Cheng Horng, Feng-Yi Yang, “Optimal Base-Stock Level of the Stochastic Economic Lot Scheduling Problem”, Proceedings of the 2013 International Conference on Computing, Management and Telecommunications, pp. 380-385, Ho Chi Minh, Vietnam, Jan. 21-24, 2013.
  24. Feng-Yi Yang*, Shih-Cheng Horng, “Ultrasound Mediated Delivery of Liposomal Doxorubicin in Mice with Glioma”, Proceedings of the 2012 International Conference on Biomedical Engineering and Biotechnology, pp.68-71, Beijing, China, OCT. 26-28, 2012.
  25. Feng-Yi Yang*, Yi-Li Lin, “Investigation of Bone Ratios for Prenatal Fetal Assessment in Taiwanese Population”, Proceedings of the 2012 International Conference on Biomedical Engineering and Biotechnology, pp.146-149, Beijing, China, OCT. 26-28, 2012.
  26. Chia-En Ko, Feng-Yi Yang*, “The Change of Permeability of Blood-Brain Barrier Opening Induced with Foucsed Ultrasound as Measured by Dynamic Gd-DTPA-Enhanced MRI”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2012.
  27. Wen-Yuan Chang, Feng-Yi Yang*, Jhih-Shian Lee, Jyh-Cheng Chen, “Image-Derived Input Functions for Small-Animal 4-Borno-2-18F-Fluoro-L-Phenylalanine PET Studies”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2012.
  28. Yi-Li Lin, Feng-Yi Yang*, “Enhanced Antitumor Effect for Boron Neuron Capture Therapy with Local Blood-Brain Barrier Disruption Induced by Focused Ultrasound”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2012.
  29. Wen-Wei Lu, Ming-Che Teng, Feng-Yi Yang*, “Combining Focused Ultrasound and Targeted Liposomal Doxorubicin for Enhanced Treatment in Glioblastoma Multiforme”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2012.
  30. Wei-Ting Lin, Ming-Che Teng, Feng-Yi Yang*, “Pharmacokinetic Evaluation of 111In-Labeled Targeted Drug in Brain Tumor after Blood-Brain Barrier Opening with Focused Ultrasound”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2012.
  31. Jium-Yu Liu, Chia-En Ko, Feng-Yi Yang*, “Dose Distribution of Drug Delivery with Blood-Brain Barrier Disruption by Focused Ultrasound”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2012.
  32. Wei-Shen Su, Ming-Che Teng, Feng-Yi Yang*, “Repeated Focused Ultrasound Enhanced Targeted Chemotherapy for Glioblastoma Multiforme”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2012.
  33. Chia-En Ko, Feng-Yi Yang*, “Analysis of the Permeability of Blood-Brain Barrier Opening Induced by Foucsed Ultrasound Using Dynamic Contrast-Enhanced MRI”, 7th International Symposium of Medical Imaging and Radiological Sciences, ROC, 2012.
  34. Wen-Yuan Chang, Feng-Yi Yang, Jhih-Shian Lee, Jia-Je Li, Yu-ling Hsieh, Hsu-Yin Tseng, Zhi-Wei Chang, Hsin-Ell Wang, Jyh-Cheng Chen, “Evaluation of Pharmacokinetics of 4-Borno-2-18F -Fluoro-L-Phenylalanine for Boron Neutron Capture Therapy in a Glioma-Bearing Rat Model with Ultrasound Induced targeted Blood-Brain Barrier Disruption”, 7th International Symposium of Medical Imaging and Radiological Sciences, ROC, 2012.
  35. Shih-Cheng Horng, Feng-Yi Yang, “Simulation-Based Meta-heuristic Approach for Booking Limits Problem at a Hotel Baby”, Proceedings of the 2012 International Conference on Information Security and Intelligent Control, pp. 153-156, Yunlin, Taiwan, Aug. 14-16, 2012 (EI)
  36. Shih-Cheng Horng, Feng-Yi Yang, “Ordinal Optimization Based Algorithm for Hotel Booking Limits Problem”, Proceedings of the International Symposium on Computer, Consumer and Control 2012, pp. 759-762, Taichung, Taiwan, June 4-6 2012 (EI)
  37. Shih-Cheng Horng, Feng-Yi Yang, “Optimal Base‐stock Policy of the Assemble to Order Systems”, Proceedings of the 17th International Symposium on Artificial Life and Robotics, pp. 816-819, Oita, Japan, Jan. 19-21 2012 (EI)
  38. Feng-Yi Yang*,Shih-Cheng Horng, “Ultrasound Enhanced Delivery of Macromolecular Agents in Brain Tumor Rat Model”, 33rd Annual International Conference IEEE Engineering in Medicine and Biology Society, pp. 5573-5576, Boston, USA, Aug. 30th- Sep. 3rd , 2011 (EI)
  39. Shih-Cheng Horng, Feng-Yi Yang, “Combining Particle Swarm with Ordinal Optimization for Stochastic Simulation Optimization Problems”, Proceedings of the 8th Asian Control Conference, pp. 982-987, Kaohsiung, Taiwan, May 15-18 2011 (EI)
  40. Shih-Cheng Horng, Feng-Yi Yang, “Apply Particle Swarm Optimization to Maximize the Service Reliability of Grid Computing System”, Proceedings of the 25th International Conference on Information Networking,  pp. 235-240,  Kuala Lumpur, Malaysia, Jan. 26-28 2011 (EI)
  41. Ming-Che Teng, Tai-Tong Wong, Feng-Yi Yang*, “Impact of focused ultrasound-enhanced doxorubicin delivery on tumor volume in mice with glioma”, 6th International Symposium of Medical Imaging and Radiological Sciences, ROC, 2011.
  42. Ming-Che Teng, Guan-Liang Lin, Feng-Yi Yang*, “Non-Invasive Quantitative the Blood-Brain Barrier Permeability by Local Enhancement of Focused Ultrasound”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2010.
  43. Feng-Yi Yang*, Wei-Hsiu Chiu, Chi-Fang Yeh, “Color doppler sonographic evaluation of peak systolic velocity and pulsatility index in artery after pulsed HIFU exposure”, International Symposiumon therapeutic ultrasound,  Tokyo Japan, 2010 (EI)
  44. Guan-Liang Lin, Ming-Che Teng, Hui-Hsien Lin, Hsin-Ell Wang, Feng-Yi Yang*, “Investigation of the effect of pulsed-HIFU on the permeability of blood-tumor barrier in rats”, 5th International Symposium of Medical Imaging and Radiological Sciences, ROC, 2010.
  45. Yu-Shi Lin, Chia-En Ko, Yi-Hsuan Kao, Feng-Yi Yang*, “The effect of repeated focused ultrasound on the permeability of blood-brain barrier”, 5th International Symposium of Medical Imaging and Radiological Sciences, ROC, 2010.
  46. Sheng-Fang Huang, Yi-An Lin, Feng-Yi Yang*, “Behavioural evaluation for blood-brain barrier disruption induced by focused ultrasound”, 5th International Symposium of Medical Imaging and Radiological Sciences, ROC, 2010.
  47. Feng-Yi Yang*, Chi-Hong Chang, “Effect of microbubble dose on the reversibility of focused-ultrasound-induced blood-brain barrier disruption”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2009.
  48. Wei-Hsiu Chiu, Guan-Liang Lin, Feng-Yi Yang*, “Functional changes in arteries induced by high-intensity focused ultrasound”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2009.
  49. Wei-Hsiu Chiu, Shih-Cheng Horng, Feng-Yi Yang*, “The length ratios between fetal natal bone and limb bones in the general population”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2009.
  50. Yu-Shi Lin, Shih-Cheng Horng, Shuo-Hui Hung, Feng-Yi Yang*, “Effect of ultrasound parameters on the duration of focused-ultrasound-induced blood-brain barrier disruption”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2009.
  51. Guan-Liang Lin, Feng-Yi Yang*, “Pulsed-HIFU enhances permeability of the blood-tumor barrier in F-98 glioma of F-344 rats”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2009.
  52. J-C. Weng, S-K. Wu, F-Y. Yang, W-L. Lin and W-Y. I. Tseng, “Determination of Pulse Sequence and Timing of Contrast-enhanced MRI for Assessing Blood-brain Barrier Disruption Following Transcranial Focused Ultrasound”, ISMRM 17th Scientific Meeting and Exhibition in Honolulu, Hawaii, USA, 2009.
  53. Shih-Cheng Horng, Feng-Yi Yang*, “An expert system for the fault diagnosis of computer hardware”, International conference on advanced information technology, ROC, 2009.
  54.  W.H. Chiu, G.L. Lin, W.H. Wang, F. Y. Yang*, “The relation between fetal nasal bone length & head circumference in Taiwanese general population”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2008.
  55. W.H. Chiu, Y.S. Lin, S.H. Hung, F. Y. Yang*, “The relationship between fetal nasal bone length and head circumference in the prenatal ultrasound examination”, 4th Conference of International Medical Imaging and Radiological Sciences, 2008.
  56. F. Y. Yang, W.M. Fu, W.S. Chen, W.L. Lin, “The Focused Ultrasound with a Contrast Agent for Non-invasive Blood-Brain Barrier Disruption”, Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2007.
  57. F.Y. Yang, W.M. Fu, W.S. Chen, W.L. Lin, “Investigation of Focused Ultrasound with a Contrast Agent on Local Blood-Brain Barrier Disruption”, International Workshop on Modeling and Simulation in Health , ROC, 2007.
  58. F.Y. Yang, W.M. Fu, W.S. Chen, W.L. Lin, “Contrast-Agent-Enhanced the disruption of blood-brain-barrier by focused ultrasound through an intact skull”, International Symposiumon therapeutic ultrasound, Seoul, Korea,2007.
  59. F.Y. Yang, W.M. Fu, H.C. Liou, W.S. Chen, W.L. Lin, “In-vivo Investigation of the Effects of Ultrasound Contrast Agent and Focused Ultrasound on Blood-Brain Barrier Disruption”, IEEE Ultrasonics Symposium, 1592-1595, Vancouver, Canada, 2006 (EI)
  60. F.Y. Yang, H.L. Liu, Y.Y. Chen,  W.L. Lin, “Beam steering at low frequencies for noninvasive brain disease therapy with a hemispherical ultrasound transducer”, Ultrasound in Medicine & Biology, Vol. 32, No. 5S, pp. 278, Seoul, Korea, 2006.
  61. F.Y. Yang, W.M. Fu, H.C. Liou, W.S. Chen, W.L. Lin, “The Investigation of Contrast-Agent Enhanced Blood-Brain Barrier Disruption”, International Symposium on Biomedical Engineering,10018, ROC, 2006.
  62. F.Y. Yang, T.J. Mao, Y.Y. Chen, H. Chang, W.L. Lin, “Beam Steering and Focusing Ability of a Contact Ultrasound Transducer for Transskull Brain Disease Therapy”, International Symposium on Biomedical Engineering,10019, ROC, 2006.
  63. F. Y. Yang, W.M. Fu, H.C. Liou, W.S. Chen, W.L. Lin, “Quantitative evaluation of contrast agent enhanced local blood-brain barrier disruption by focus ultrasound,” Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2006.
  64. F. Y. Yang, H.L. Liou, Y.Y. Chen, W.L. Lin, “Beam Steering at Low Frequencies for Noninvasive Brain Disease Therapy with a Hemispherical Ultrasound Transducer,” Proceeding of the Annual Conference of the Biomedical Engineering Society, ROC, 2006.
  65. S.C. Horng, S.Y. Lin, M.H. Cheng, F.Y. Yang, C.H. Liu, W.Y. Lee, C.H. Tsai, “Reducing the Overkills and Retests in Wafer Testing Process”, IEEEI/SEMI Advanced Semiconductor Manufacturing Conference and Workshop, pp.286-291, 2003 (EI)
  66. H. H. Chang, F. Y. Yang, Y. J. Tseng, W. C. Chu, W. Y. Chung, D. H. C. Pan, “A PC-Based Dose Calculation System for Gamma Knife Stereotactic Radiosurgery,” Proceeding of the Annual Conference of the Biomedical Engineering Society, pp.24-25, ROC, 1997.

Book

Feng-Yi Yang, Sonography, Principles and Instruments (ELSEVIER TAIWAN LLC)

Patents

  1. Feng-Yi Yang, An Ultrasound Generator for Inhibiting Intestinal Inflammatory Factor and/or Improving Neuroinflammation and its System and Method Thereof. (US Patent No.: 18/194,743)
  2. 楊逢羿, 抑制腸道發炎因子及/或改善神經發炎之超音波產生裝置及系統. (ROC發明專利申請案號: 111147845)
  3. Feng-Yi Yang, Ultrasound stimulation helmet. (US Patent No.: US10940335 B2, 專利權起迄日: 2021/03/09–2036/11/23)
  4. 楊逢羿, 超音波刺激頭盔. (中國專利號: 201580083270.6, 專利權起迄日: 2020/09/28–2035/10/14)
  5. 楊逢羿, 超音波刺激頭盔. (日本證書號: 特許第6670485號, 專利權起迄日: 2020/03/04–2035/10/14)
  6. 楊逢羿, 用於治療及／或預防神經退化性疾病的低強度脈衝式超音波器具. (ROC證書號: I 615172, 專利權起迄日: 2018/02/21–2034/09/03)
  7. Feng-Yi Yang, I-Fang Chung, Sheng-Yao Huang, Blood-Brain Barrier Recovery Curve Assessment Method and System. (US Patent No.: US9291692 B2, Published date: 2016-03-22)
  8. 楊逢羿, 鍾翊方, 黃聖堯, 血腦障壁恢復曲線之評估方法及系統. (ROC證書號: I 489307, 專利權起迄日: 2015/06/21–2033/09/05)
  9. Feng-Yi Yang, Methods and system for ultrasound-mediated drug delivery. (US Patent No.: US9072879 B2, Date of Patent: 2015-07-07)
  10. Feng-Yi Yang, Wei-Hsiu Chiu, Synchronic monitor system for drug delivery induced by ultrasound and the method thereof. (US Patent No.: US2012/0010502 A1, Published date: 2012-01-12)
  11. 楊逢羿, 邱偉修, 同步監控超音波導引藥物傳輸機制的系統及其方法. ( ROC證書號: I 454247, 專利權起迄日: 2014/10/01–2030/07/08)
  12. Yang, Feng-Yi, Method and apparatus for dispensing fluid doses. (US Patent No.: US6595390, Published date: 2003-07-22)
  13. Yang, Feng-Yi, Microelectronic fabrication die electrical probe apparatus electrical test method providing enhanced microelectronic fabrication die electrical test accuracy and efficiency. (US Patent No.: US6440757, Published date: 2002-08-27)
  14. Yang, Feng-Yi, Method and apparatus for calibrating a dissolved oxygen analyzer. (US Patent No.: US6330819, Published date: 2001-12-18)
  15. Yang, Feng-Yi, Huang, Wei-tien, Apparatus and method for monitoring fluorine ions. (US Patent No.: US6306284, Published date: 2001-10-23)
  16. Yang, Feng-Yi, Apparatus for sensing liquid level. (US Patent No.: US6067854, Published date: 2000-05-30)
  17. 楊逢羿, 一種高效率之晶片探針測試方法. (ROC證書號: 206098, 專利權起迄日: 2004/06/21–2021/10/18
  18. 楊逢羿, 連續式氟離子監測裝置. ( ROC證書號: 218126, 專利權起迄日: 2004/01/11–2011/01/25)
  19. 楊逢羿, 具有自動校正功能的溶氧分析儀. ( ROC證書號: 173937, 專利權起迄日: 2001/05/16–2011/06/29)
  20. 楊逢羿, 廢水處理系統之加藥監測裝置. ( ROC證書號: 162325, 專利權起迄日: 2000/08/01–2010/11/05)
  21. 楊逢羿, 組合式液位控制開關. ( ROC證書號: 150487, 專利權起迄日: 1999/08/01–2010/11/09)

office： 實驗大樓 B322室
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