主要學歷
| 畢/肄業學校 | 國別 | 主修系別 | 學位 | 起 | 迄 |
| University of Rochester | 美國 | Pathology and Laboratory Medicine | 博士 | 1998/9/1 | 2003/6/30 |
| 國立清華大學 | 中華民國 | 輻射生物研究所 | 碩士 | 1993/9/1 | 1995/6/30 |
| 國立中興大學 | 中華民國 | 食品科學系 | 學士 | 1989/9/1 | 1993/6/30 |
現職及與專長相關之經歷
| 服務單位 | 服務部門 | 職稱 | 服務期間起 | 服務期間迄 |
| 國立陽明大學 | 生物醫學影像暨放射科學系 | 教授 | 2014/2/1 | |
| 國立陽明大學 | 生物醫學影像暨放射科學系 | 副教授 | 2010/2/1 | 2014/1/31 |
| 國立陽明大學 | 生物醫學影像暨放射科學系 | 助理教授 | 2006/2/1 | 2010/1/31 |
| 國家衛生研究院 | 技術移轉室 | 副管理師 | 2005/4/1 | 2006/1/31 |
| 耶魯大學 | Therapeutic Radiology | 博士後研究員 | 2004/3/1 | 2005/2/28 |
| University of Medicine and Dentistry of New Jersey | Cancer Institute of New Jersey | 博士後研究員 | 2003/2/1 | 2004/2/28 |
| 食品工業發展研究所 | 菌種中心 | 副研究員 | 1995/8/1 | 1998/7/31 |
專長
放射分子腫瘤學Molecular radiation oncology
放射生物學Radiation Biology
分子細胞生物學Molecular Cell Biology
分子基因影像Molecular Genetic Imaging
研究成果
(Ａ) 期刊發表(使用數據:JCR edition 2019年)
| 1. | Cheng-Han Tsai, Chun-Yuan Chang, Bing-Ze Lin, Yu-Lou Wu, Meng-Hsiu Wu, Liang-Ting Lin, Wen-Chien Huang, Jonathan D. Holz, Tzong-Jen Sheu, Jhih-Shian Lee, Richard N. Kitsis, Pei-Han Tai, Yi-Jang Lee. Up-regulation of cofilin-1 in cell senescence associates with morphological change and p27kip1 mediated growth delay (In Press). Aging Cell 2021; 20(1):e13288 (SCI). (Impact factor: 7.238;Rank: 4.90%)第十作者(通訊)作者 |
| 2. | Shan-Ying Wang, Liang-Ting Lin, Bing-Ze Lin, Chi-Hsien Chang, Chun-Yuan Chang, Min-Ying Lin, Yi-Jang Lee. A Comparative Study of Single or Dual Treatment of Theranostic 188Re-Liposome on MicroRNA Expressive Profiles of Orthotopic Human Head and Neck Tumor Model. Heighpubs Otolaryngology and Rhinology 2021; 5:001-012 (OI). 第七作者(通訊)作者 |
| 3. | Jyh-Der Leu, Chung-Yih Wang, Chia-Chen Lo, Min-Ying Lin, Chun-Yuan Chang, Wen-Chin Hung, Shi-Ting Lin, Bo-Shen Wang, and Yi-Jang Lee. Involvement of c-Myc in low dose radiation-induced senescence enhanced migration and invasion of unirradiated cancer cells. Aging 2021; 13: (SCI). 第九作者(通訊)作者 |
| 4. | Yi-Xuan Li, Shih-Po Su, Chou-Hsun Yang, Ming-Ho Liu, Pin-Ho Lo, Yi-Chen Chen, Chao-Ping Hsu, Yi-Jang Lee, Huihua Kenny Chiang, Yang-Hsiang Chan. Molecular Design of Ultrabright Semiconducting Polymer Dots with High NIR-II Fluorescence for 3D Tumor Mapping. Advanced Healthcare Materials 2021; 2100993:1-10 (SCI). (Impact factor: 7.367;Rank: 7.47%)第八作者(通訊)作者 |
| 5. | Min-Ying Lin, Hsin-Hua Hsieh, Jyh-Cheng Chen, Chuan-Lin Chen, Nin-Chu Sheu, Wen-Sheng Huang, Shinn-Ying Ho, Ting-Wen Chen, Yi-Jang Lee *, Chun-Yi Wu *. Brachytherapy Approach Using 177Lu Conjugated Gold Nanostars and Evaluation of Biodistribution, Tumor Retention, Dosimetry and Therapeutic Efficacy in Head and Neck Tumor Model (Accepted). Pharmaceutics 2021; : (SCI). (Impact factor: 4.421;Rank: 16.05%)第九作者(通訊)作者 |
| 6. | Min-Ying Lin, Yu-Chan Chang, Shan-Ying Wang, Muh-Hwa Yang, Chih-Hsien Chang, Michael Hsiao, Richard N. Kitsis, Yi-Jang Lee. OncomiR miR-182-5p enhances radiosensitivity by inhibiting the radiation-induced antioxidant effect through SESN2 in head and neck cancer. Antioxidants 2021; 10:1808 (SCI). (Impact factor: 5.014;Rank: 6.84%)第八作者(通訊)作者 |
| 7. | Bing-Ze Lin, Shen-Ying Wan, Min-Ying Lin, Chi-Hsien Chang, Ting-Wen Chen, Muh-Hwa Yang, Yi-Jang Lee. Involvement of Differentially Expressed microRNAs in the PEGylated Liposome Encapsulated 188Rhenium-Mediated Suppression of Orthotopic Hypopharyngeal Tumor. MOLECULES 2020; 25(16):3609 (SCI). (Impact factor: 3.267;Rank: 39.27%)第七作者(通訊)作者 |
| 8. | Xiang-Yun Lan, Tzu-Ting Chung, Chien-Ling Huang, Yi-Jang Lee, Wan-Chun Li. Traditional Herbal Medicine Mediated Regulations during Head and Neck Carcinogenesis. Biomolecules 2020; 10(9):1321 (SCI). (Impact factor: 4.082;Rank: 32.83%)第四作者以後作者 |
| 9. | Wei-Hsiang Hsu, Bing-Ze Lin, Jey-Der Leu, Pin-Ho Lo, Hsueh-Yen Yu, Chao-Tsung Chen, Yuan-Heng Tu, Yun-Lian Lin and Yi-Jang Lee. Involvement of 8-O-acetylharpagide for Ajuga taiwanensis mediated suppression of senescent phenotypes in human dermal fibroblasts. Scientific Reports 2020; 10(1):19731 (SCI). (Impact factor: 3.998;Rank: 23.24%)第九作者(通訊)作者 |
| 10. | Ching-Hsiang Chiu, Jyh-Der Leu, Tzu-Ting Lin, Pin-Hua Su, Wan-Chun Li, Yi-Jang Lee, Da-Chuan Cheng. Systematic quantification of cell confluence in human normal oral fibroblasts (In Press) . Applied Sciences-Basel 2020; : (SCI). (Impact factor: 2.474;Rank: 34.62%)第六作者(通訊)作者 |
| 11. | CHUN-YUAN CHANG, SHI-ONG CHANG, JYH-DER LEU, YU-CHAN CHANG, MICHAEL HSIAO, LIANG-TING LIN, HAN-NAN LIN and YI-JANG LEE. Comparison of cofilin-1 and Twist-1 protein expression in human non-small cell lung cancer tissues. Oncology Reports 2019; 42(2):805-816 (SCI). (Impact factor: 3.417;Rank: 46.93%)第八作者(通訊)作者 |
| 12. | Chung-Yih Wang, Chun-Yuan Chang, Chun-Yu Wang, Kaili Liu, Chia-Yun Kang, Yi-Jang Lee *, Wei R Chen. N-dihydrogalactochitosan potentiates radiosensitivity of liver metastatic tumor cells originated from murine breast tumors. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2019; 20(22):5581-5596 (SCI). (Impact factor: 4.556;Rank: 24.75%)第六作者(通訊)作者 |
| 13. | Liang-Tin Lin, Shin-Yi Liu, Jyh-Der Leu, Cheng-Yuan Chang, Shih-Hwa Chiou, Te-Chang Lee, Yi-Jang Lee. Arsenic trioxide-mediated suppression of miR-182-5p is associated with potent anti-oxidant effects through up-regulation of SESN2. Oncotarget 2018; 9:16028-16042 (OI). (Impact factor: 5.168;Rank: 20.05%)第一作者/通訊作者(通訊)作者 |
| 14. | Chun-Yuan Chang, Chao-Cheng Chen, Liang-Ting Lin, Chi-Hsien Chang, Liang-Chen Chen, Hsin-Ell Wang, Te-Wei Lee and Yi-Jang Lee,. PEGylated liposome encapsulated rhenium-188 radiopharmaceutical inhibits proliferation and epithelial-mesenchymal transition of human head and neck cancer cells in vivo with repeated therapy . Cell Death Discovery 2018; 4(100): (SCI). (Impact factor: 4.114;Rank: 38.72%)第四作者以後(通訊)作者 |
| 15. | Chao-Cheng Chen, Jia-Je Li, Nai-Hua Guo, Deng-Yuan Chang, Chung-Yih Wang, Jenn-Tzong Chen, Wuu-Jyh Lin, Kwan-Hwa Chi, Yi-Jang Lee, Ren-Shyan Liu *, Chuan-Lin Chen *, Hsin-Ell Wang *. Evaluation of the biological behavior of a gold nanocore-encapsulated human serum albumin nanoparticle (Au@HSANP) in a CT-26 tumor/ascites mouse model after intravenous/intraperitoneal administration (Accepted). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2018; : (SCI). (Impact factor: 4.556;Rank: 24.75%)第四作者以後作者 |
| 16. | Yi-Jang Lee. Revisit the Effects of Low Dose Radiation in Diagnosis and Therapy. Clinics in Oncology 2017; 2:1206 (OI). 單一作者作者 |
| 17. | JYH-DER LEU, HSIN-YU CHIU, CHUN-YUAN CHANG, YI-JANG LEE* and WEI R. CHEN. Combination of Radiofrequency Ablation and Glycated Chitosan as Treatment on a Syngeneic Breast Tumor Model. ANTICANCER RESEARCH 2017; 37(6):2965-2974. (SCI). (Impact factor: 1.994;Rank: 82.99%)第四作者以後(通訊)作者 |
| 18. | Chia-Ming Chang, Keng-Li Lan, Wen-Sheng Huang, Yi-Jang Lee, Te-Wei Lee, Chih-Hsien Chang, Chi-Mu Chuang. 188Re-liposome can induce mitochondrial autophagy and reverse drug resistance for ovarian cancer: from bench evidence to preliminary clinical proof-of-concept . INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2017; 18(5):E903 (SCI). (Impact factor: 4.556;Rank: 24.75%)第四作者以後作者 |
| 19. | Jyh-Der Leu, Bo-Shen Wang, Shu-Jun Chiu, Chung-Yun Chang, Chien-Chih Chen, Fu-Du Chen, Shiirevnyamba Avirmed, and Yi-Jang Lee. Combination of fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in the xenograft tumor model (In Press). Oncology Letters 2016; :4975-4982 (SCI). (Impact factor: 2.311;Rank: 74.39%)第一作者/通訊作者作者 |
| 20. | Syue-Liang Lin, Tse-Ying Liu, Chun-Liang Lo, Bo-Sheng Wang, Yi-Jang Lee, Kai-Ying Lin, C.Allen Chang. Synthesis, surfacemodification,andphotophysicalstudiesofLn2O2S: Ln’3þ (Ln¼Gd, Tb,Eu;Ln’¼Tb and/orEu)nanoparticles for luminescencebioimaging. JOURNAL OF LUMINESCENCE 2016; 175:165-175 (SCI). (Impact factor: 3.28;Rank: 21.13%)第四作者以後作者 |
| 21. | Hung-Mu Wei, Li-Chih Lin, Chiu-Feng Wang, Yi-Jang Lee, Yuan-Tsong Chen, and You-Di Liao. Antimicrobial Properties of 15 kDa Human Granulysin against Pseudomonas aeruginosa (Accepted). PLoS One 2016; : (SCI). (Impact factor: 2.74;Rank: 37.32%)第四作者以後作者 |
| 22. | Yao An Shen, Keng Li Lan, Chih Hsien Chang, Liang Ting Lin, Chun Lin He, Po Hung Chen, Te Wei Lee, Yi Jang Lee, Chi Mu Chuang. Intraperitoneal 188Re-Liposome delivery switches ovarian cancer metabolism from glycolysis to oxidative phosphorylation and effectively controls ovarian tumour growth in mice. RADIOTHERAPY AND ONCOLOGY 2016; :S0167-8140(16)00065-7 (SCI). (Impact factor: 4.856;Rank: 12.31%)第四作者以後作者 |
| 23. | Chung-Yih Wang, Cheng-Han Tsai, Chun-Yuan Chang, Man-Jyun Liao, Ren-Shyan Liu, and Yi-Jang Lee. Over-expression of cofilin-1 suppressed mobility of lung cancer cells is associated with down-regulation of SNAIL-1 and induction of let-7 (Accepted). CLINICS IN ONCOLOGY 2016; : (OI). 第一作者/通訊作者作者 |
| 24. | Shiirevnyamba Avirmed, Bo-Shen Wang, Baasansuren Selenge, Amarsaikhan Sanjaajamts, Batmunkh Ganbat, Ulziisaikhan Erdenebile, Myagmarsuren Purevsure, Sarantsetseg Jigjidsuren, Munkhbat Batmunkh, Yi-Jang Lee. Association of MDM2-SNP309 and p53R72P polymorphisms with the risk of bladder cancer among Mongolians (Accepted). Molecular Clinical Oncology 2016; : (OI). 第一作者/通訊作者作者 |
| 25. | Liang-Ting Lin , Chun-Yuan Chang , Chi-Hsien Chang , H.E. WANG , Shih-Hwa Chiou , Ren-Shyan Liu , Te-Wei Lee, Yi-Jang Lee.. Involvement of let-7 microRNA for the therapeutic effects of Rhenium-188-embedded liposomal nanoparticles on orthotopic human head and neck cancer model. Oncotarget 2016; 7(40):65782–65796 (SCI). (Impact factor: 5.168;Rank: 20.05%)第一作者/通訊作者作者 |
| 26. | Cheng-Han Tsai; Liang-Ting Lin; Chung-Yih Wang; Yu-Wen Chiu; Yen-Ting Chou; Shu-Jun Chiu; Hsin-Ell Wang; Ren-Shyan Liu; Chung-Yi Wu; Pei-Chia Chan; Muh-Hwa Yang; Shih-Hwa Chiou; Man-Jyun Liao; Yi-Jang Lee. Over-expression of cofilin-1 suppressed growth and invasion of cancer cells is associated with up-regulation of let-7 microRNA . BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2015; 1852(5):851-861 (SCI). (Impact factor: 4.352;Rank: 19.01%)第一作者/通訊作者作者 |
| 27. | Chun-Yuan Chang, Jyh-Der Leu, Yi-Jang Lee. The actin depolymerizing factor (ADF)/cofilin signaling pathway and DNA damage responses in cancer . INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2015; 16(2):4095-4120 (SCI). (Impact factor: 4.556;Rank: 24.75%)第一作者/通訊作者作者 |
| 28. | Guo HW, Lin LT, Chen PH, Ho MH, Huang WT, Lee YJ, Chiou SH, Hsieh YS, Dong CY, Wang HW. Low-fluence rate, long duration photodynamic therapy in glioma mouse model using organic light emitting diode (OLED). Photodiagnosis and Photodynamic Therapy 2015; : (SCI). (Impact factor: 2.894;Rank: 58.81%)第四作者以後作者 |
| 29. | Baasansuren S, Po-Shen Wang, Ulziisaikhan E, Amarsaukhan S, Yi-Jang Lee, Shiirevnyamba A. Association between MDM2-SNP309 polymorphism and bladder cancer in Mongolians. Journal of Mongolian Medical Sciences 2015; 1(171):4-8 (OI). 第四作者以後作者 |
| 30. | Yao-Huei Huang, Pei-Ming Yang, Qiu-Yu Chuah, Yi-Jang Lee, Yi-Fen Hsieh, Chih-Wen Peng and Shu-Jun Chiu. Autophagy promotes radiation-induced senescence but inhibits bystander effects in human breast cancer cells (Accepted). Autophagy 2014; : (SCI). (Impact factor: 9.77;Rank: 11.03%)第四作者以後作者 |
| 31. | Ying-Ling Chen, Chung-Yih Wang, Feng-Yi Yang, Bo-Sheng Wang, Jason Y. Chen, Liang-Ting Lin, Jyh-Der Leu, Su-Jun Chiu, Fu-Du Chen, Yi-Jang Lee# , and Wei R. Chen#. Synergistic effects of the immunoadjuvant glycated chitosan with high-intensity focused ultrasound on suppression of metastases in a syngeneic breast tumor model . Cell Death & Disease 2014; : (SCI). (Impact factor: 6.304;Rank: 20.26%)第一作者/通訊作者作者 |
| 32. | Shu-Jun Chiu, En-Chi Liao, Ying-Ting Hsu, Qiu-Yu Chuah, Yi-Jang Lee, Jing-Yi Hu, Tsui-Chin Huang, and Pei-Ming Yang. Radiation induces senescence and a bystander effect through metabolic alterations . Cell Death & Disease 2014; : (SCI). (Impact factor: 6.304;Rank: 20.26%)第四作者以後作者 |
| 33. | Liang-Ting Lin, Chih-Hsien Chang, Hsiang-Lin Yu, Ren-Shyan Liu, Hsin-Ell Wang, Shu-Jun Chiu, Fu-Du Chen, Te-Wei Lee, Yi-Jang Lee. Evaluation of the therapeutic and diagnostic effects of PEGylated liposomes embedded rhenium-188 on human non-small cell lung cancer using the small animal model . Journal of Nuclear Medicine 2014; 55(11):1864-1870 (SCI). (Impact factor: 7.887;Rank: 2.61%)第九作者(通訊)作者 |
| 34. | Liang-Ting Lin, Shih-Hwa Chiou, Te-Wei Lee, Ren-Shyan Liu, Jeng-Jong Hwang, Chih-Hsien Chang, Hsin-I Ma, Yi-Jang Lee. A comparative study of primary and recurrent human glioblastoma multiforme using the small animal imaging and molecular expressive profiles . MOLECULAR IMAGING AND BIOLOGY 2013; 15(3):262-272 (SCI). (Impact factor: 2.925;Rank: 31.72%)第一作者/通訊作者作者 |
| 35. | Jyh-Der Leu, Yu-Wen Chiu, Chia-Chien Lo, Pei-Hsun Chiang, Su-Jun Chiu, Cheng-Han Tsai, Jeng-Jong Hwang, Ran-Chou Chen, Vera Gorbunova, Yi-Jang Lee. Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity . INTERNATIONAL JOURNAL OF RADIATION BIOLOGY 2013; 89(6):433-444 (SCI). (Impact factor: 2.368;Rank: 7.35%)第一作者/通訊作者作者 |
| 36. | Wei-Hsun Wang, I-Tsang Chiang, Yu-Chang Liu, Fei-Ting Hsu, Hong-Wen Chen, Chuan-Lin Chen, Yi-Jang Lee, Wuu-Jyh Lin and Jeng-Jong Hwang. Simultaneous Imaging of Temporal Changes of NF-κB Activity and Viable Tumor Cells in Huh7/NF-κB-tk-luc2/rfp Tumor-bearing Mice . In Vivo 2013; 27(3):339-350 (SCI). (Impact factor: 1.541;Rank: 79.50%)第四作者以後作者 |
| 37. | Yi-Chu Yu, Pei-Ming Yang, Qiu-Yu Chuah, Yao-Huei Huang, Chih-Wen Peng, Yi-Jang Lee, Shu-Jun Chiu. Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways (DOI: 101038/srep01675). Scientific Reports 2013; 3(1675):1-11 (SCI). (Impact factor: 3.998;Rank: 23.24%)第四作者以後作者 |
| 38. | Ying-Feng Chang, Cheng-Han Chao, Lih-Yuan Lin, Cheng-Han Tsai, Chien Chou and Yi-Jang Lee. Determination of urine cofilin-1 level in acute kidney injury using a high-throughput fiber optic biosensor . JOURNAL OF BIOMEDICAL OPTICS 2013; 19(1):011004-1 – 011004-6 (SCI). (Impact factor: 2.785;Rank: 29.38%)第一作者/通訊作者作者 |
| 39. | Liang-Ting Lin, Bo-Sheng Wang, Jyh-Cheng Chen, Chi-Hsien Liu, Chien Chou, Shu-Jun Chiu, Wen-Yi Chang, Ren-Shyan Liu, C. Allen Chang, and Yi-Jang Lee. mPlum-IFP 14 fluorescent fusion protein may display Forster resonance energy transfer associated properties that can be used for near-infrared based reporter gene imaging. JOURNAL OF BIOMEDICAL OPTICS 2013; 18 (12):126013 (SCI). (Impact factor: 2.785;Rank: 29.38%)第一作者/通訊作者作者 |
| 40. | Li-hsin Chen, Pei-ming Chu, Yi-jang Lee, Pang-hsien Tu, Chin-wen Chi, Hsin-chen Lee , Shih-hwa Chiou *. Targeting protective autophagy exacerbates UV-triggered apoptotic cell death (Accepted). INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2012; 13(1):1209-24 (SCI). (Impact factor: 4.556;Rank: 24.75%)第三作者作者 |
| 41. | Cheng-Han Chao, Ying-Feng Chang, Hsien-Ching Chen, Lih-Yuan Lin, Pei-Chun Yu, Yu-Sun Chang, Yi-Jang Lee and Chien Chou. Detection of urine cofilin-1 from patients hospitalized in the intensive care unit using the metal-enhanced fluorescence technique . SENSORS AND ACTUATORS B-CHEMICAL 2012; 173:184-190 (SCI). (Impact factor: 7.1;Rank: 2.34%)第一作者/通訊作者作者 |
| 42. | Shanshan Shi, Tianfang Li, Jonathan Holz, Yi-Jang Lee, Tzong-jen Sheu, Tao Xiao, Meng Mi. TIMP2 Deficient Mice Develop Accelerated Osteoarthritis via Promotion of Angiogenesis upon Destabilization of the Medial Meniscus (Accepted). BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2012; 423(2):366-372 (SCI). (Impact factor: 2.985;Rank: 35.92%)第四作者以後作者 |
| 43. | Ying-Ling Chen, Shiau-Yi Wang, Ren-Shyan Liu, Hsin-Ell Wang, Jyh-Cheng Chen, Shih-Hwa Chiou, C. Allen Chang, Liang-Ting Lin,David Tan Tap Wei and Yi-Jang Lee. Remnant living cells that escape cell loss in late-stage tumors exhibit cancer stem cells-like characteristics (Accepted). Cell Death & Disease 2012; 3:e399 (SCI). (Impact factor: 6.304;Rank: 20.26%)第一作者/通訊作者作者 |
| 44. | Shin-Yi Liu, Yi-Jang Lee, Te-Chang Lee. Association of platelet-derived growth factor receptor accumulation with increased oxidative stress and cellular injury in sestrin 2 silenced human glioblastoma cells. FEBS LETTERS 2011; 585(12):1853-1858 (SCI). (Impact factor: 3.057;Rank: 33.10%)第一作者/通訊作者作者 |
| 45. | Pei-Ming Chu, Shih-Hwa Chiou, Tsann-Long Su, Yi-Jang Lee, Li-Hsin Chen, Yi-Wei Chen, Sang-Hue Yen, Ming-Teh Chen, Ming-Hsiung Chen, Yang-Hsin Shih, Pang-Hsien Tu and Hsin-I Ma. Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response . Radiation Oncology 2011; 6(7):1-13 (SCI). (Impact factor: 2.817;Rank: 34.70%)第二作者作者 |
| 46. | Cheng-Han Tsai and Yi-Jang Lee. Focus on ADF/cofilin: beyond actin cytoskeletal regulation (Accepted). ISRN Cell Biology 2011; 2012:1-7 (OI). 第一作者/通訊作者作者 |
| 47. | Jyh-Der Leu, Chung-Yih Wang, Han-Yi Tsai, I-Feng Lin, Ran-Chou Chen and Yi-Jang Lee. Involvement of p53 R72P polymorphismin the association of MDM2-SNP309 with breast cancer . ONCOLOGY REPORTS 2011; 25:1755-1763 (SCI). (Impact factor: 3.417;Rank: 46.93%)第一作者/通訊作者作者 |
| 48. | Ying-Feng Chang, Li-Chen Su*, Yi-Jang Lee, Ying-Chang Li, Yi-Tsen Lu, Jo-Ping Hsieh, Ja-An Annie Ho, Chii-Chang Chen, Cheng-Chung Lee, Chien Chou. Discrimination of Breast Cancer by Measuring Prostate-Specific Antigen Levels in Women’s Serum. ANALYTICAL CHEMISTRY 2011; 83(13):5324-5328 (SCI). (Impact factor: 6.785;Rank: 7.56%)第三作者作者 |
| 49. | Tien-Heng Huang, Shu-Jun Chiu, Pei-Hsiuang Chiang, Wen-Tai Li, Shih-Hwa Chiou, and Chiung-Tong Chen, Yi-Jang Lee. Anti-proliferative effects of N-heterocyclic indolyl glyoxylamides derivatives on human lung cancer cells . ANTICANCER RESEARCH 2011; 31:3407-3416 (SCI). (Impact factor: 1.994;Rank: 82.99%)第一作者/通訊作者作者 |
| 50. | Li-Hsin Chen, Che-Chuan Loong, Tsann-Long Su, Yi-Jang Lee, Pei-Ming Chu, Ming-Long. Autophagy inhibition enhances apoptosis triggered by BO-1051, an N-mustard derivative, and involves the ATM signaling pathway (Accepted). BIOCHEMICAL PHARMACOLOGY 2010; : (SCI). (Impact factor: 4.96;Rank: 9.78%)第四作者以後作者 |
| 51. | Shin-Yi Liu, Chin-Ya Wen, Yi-Jan Lee, and Te-Chang Lee. XPC Silencing Sensitizes Glioma Cells to Arsenic Trioxide via Increased Oxidative Damage (Accepted). TOXICOLOGICAL SCIENCES 2010; : (SCI). (Impact factor: 3.703;Rank: 17.94%)第三作者作者 |
| 52. | Sz-Hsien Yu; Yi-Jang Lee; Jui-Hung Yen; Yu-Jia Tsai; Ching-Hui Hsiao; Wen-Lin Shih; Shu-Jun Chiu. ENHANCEMENT OF p53-MUTANT HUMAN COLORECTAL CANCER CELLS RADIOSENSITIVITY BY FLAVONOID FISETIN . INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 2010; 77(5):1527-1535 (SCI). (Impact factor: 5.859;Rank: 7.09%)第二作者作者 |
| 53. | Li-Chen Su, Ran-Chou Chen, Ying-Chang Li, Ying-Feng Chang, Yi-Jang Lee, Cheng-Chung Lee and Chien Chou. Detection of Prostate-Specific Antigen with a Paired Surface Plasma Wave Biosensor ( [Epub ahead of print]). ANALYTICAL CHEMISTRY 2010; 82(9):3714-3718 (SCI). (Impact factor: 6.785;Rank: 7.56%)第四作者以後作者 |
| 54. | Yi-Jang Lee, Mien-Sheng Chu, and Shih-Che Hung. Involvement of Notch1 inhibition in serum-stimulated glia and oligodendrocyte differentiation from human mesenchymal stem cells (Accepted). Stem Cells and Cloning: Advances and Applications 2010; : (OI). 第一作者/通訊作者作者 |
| 55. | Wen-Shu Chen(co-first), Yi-Chu Yu (co-first),Yi-Jang Lee, Ji-Hshiung Chen, Hsue-Yin Hsu and Shu-Jun Chiu. DEPLETION OF SECURIN INDUCES SENESCENCE AFTER IRRADIATION AND ENHANCES RADIOSENSITIVITY IN HUMAN CANCER CELLS REGARDLESS OF FUNCTIONAL P53 EXPRESSION (Accepted). International Journal of Radiation Oncology, Biology, Physics 2009; :(In Press) (SCI). (Impact factor: 5.859;Rank: 7.09%)第三作者作者 |
| 56. | Mitsuhiro Matsuzawa, Tzong-Jen Sheu, Yi-jang Lee, Mo Chen, Tian-Fang Li, Chia Taw Huang, Jonathan Holz, J. Edward Puzas. Putative Signaling Action of Amelogenin Utilizes the Wnt/beta-Catenin Pathway . JOURNAL OF PERIODONTAL RESEARCH 2009; 44:289-296 (SCI). (Impact factor: 2.926;Rank: 13.74%)第三作者作者 |
| 57. | Yi-Jang Lee, Cheng-Han Tsai, Jeng-Jong Hwang, Shu-Jun Chiu, Tzong-Jen Sheu, and Peter C. Keng. Involvement of a p53-independent and post-transcriptional up-regulation for p21WAF/CIP1 following destabilization of the actin cytoskeleton . INTERNATIONAL JOURNAL OF ONCOLOGY 2009; 34(2):581-589 (SCI). (Impact factor: 3.899;Rank: 37.50%)第一作者/通訊作者作者 |
| 58. | Ying-Fang Sun, Jyh-Der Leu, Su-Mei Chen, I-Feng Lin and Yi-Jang Lee. Results based on 124 cases of breast cancer and 97 controls from Taiwan suggest that the single nucleotide polymorphism (SNP309) in the MDM2 gene promoter is associated with earlier onset and increased risk of breast cancer . BMC Cancer 2009; 9(13):1-13 (SCI). (Impact factor: 3.15;Rank: 52.66%)第一作者/通訊作者作者 |
| 59. | Cheng-Han Tsai, Shu-Jun Chiu, Chih-Chao Liu, Tzong-Jen Sheu, Chia-Hung Hsieh, Peter C. Keng, and Yi-Jang Lee. Regulated expression of cofilin and the consequent regulation of p27kip1 are essential for G1 phase progression . CELL CYCLE 2009; 8(15):2365-2374 (SCI). (Impact factor: 3.699;Rank: 48.97%)第一作者/通訊作者作者 |
| 60. | Chia-Hung Hsieh, Jung-Wen Kuo, Yi-Jang Lee, Chi-Wei Chang and Ren-Shyan Liu. A New Mutant TKGFP Fusion Reporter Gene for Real-time Imaging of Temporal Dynamics and Spatial Heterogeneity of HIF-1 Signal Transduction Activity mediating Hypoxia and Reoxygenation in Tumors in Living mice . JOURNAL OF NUCLEAR MEDICINE 2009; 50:2049-2057 (SCI). (Impact factor: 7.887;Rank: 2.61%)第三作者作者 |
| 61. | Shu-Jun Chiu, Yi-Jang Lee, Tzu-Sheng Hsu and Wen-Shu Chen. Oxaliplatin induced gamma-H2AX is associated with p53- and caspase-dependent apoptosis but not G2/M cell cycle arrest in human colorectal cancer cells (In Press). CHEMICO-BIOLOGICAL INTERACTIONS 2009; : (SCI). (Impact factor: 3.723;Rank: 16.85%)第二作者作者 |
| 62. | Jyh-Der Leu, I-Feng Lin, Ying-Fang Sun, Su-Mei Chen, Chih-Chao Liu and Yi-Jang Lee. The association between MDM2-SNP309 and hepatocellular carcinoma in the Taiwanese population . WORLD JOURNAL OF Gastroenterology 2009; 15(44):5592-5597 (SCI). (Impact factor: 3.665;Rank: 39.21%)第一作者/通訊作者作者 |
| 63. | Yu-Chuan Lin, Hong-Wen Chen, Yu-Cheng Kuo, Ya-Fang Chang, Yi-Jang Lee, Jeng-Jong Hwang. Therapeutic efficacy evaluation of curcumim on human oral squamous cell carcinoma xenograft using multimodalities of molecular imaging (In Press). AMERICAN JOURNAL OF CHINESE MEDICINE 2009; : (SCI). (Impact factor: 3.682;Rank: 12.50%)第四作者以後作者 |
| 64. | Ying-Feng Chang, Ran-Chou Chen, Yi-Jang Lee, Shu-Chen Chao, Li-Chen Sue, Ying-Chang Li, Chien Chou. Localized surface plasmon coupled fluorescence fiber-optic biosensor for alpha-fetoprotein detection in human serum. BIOSENSORS & BIOELECTRONICS 2008; 24(6):1610-1614 (SCI). (Impact factor: 10.257;Rank: 0.58%)第三作者作者 |
| 65. | Shu-Jun Chiu, Jui-I Chao, Yi-Jang Lee and Tzu-Shen Hsu. Regulation of gamma-H2AX formation and securin contribute to a sustained apoptosis induced by oxaliplatin via a p38 MAPK-dependent pathway in human colorectal cancer cells . TOXICOLOGY LETTERS 2008; 179(2):63-70 (SCI). (Impact factor: 3.569;Rank: 21.20%)第三作者作者 |
| 66. | Chia-Hung Hsieh, Fu-Du Chen, Hsin-Ell Wang, Jeng-Jong Hwang, Chi-Wei Chang, Yi-Jang Lee, Juri G Gelovani, Ren-Shyan Liu. Generation of Destabilized Herpes Simplex Virus type 1 Thymidine Kinase as Transcription Reporter for PET Reporter Systems in Molecular-Genetic Imaging . JOURNAL OF NUCLEAR MEDICINE 2008; 49(1):142-150 (SCI). (Impact factor: 7.887;Rank: 2.61%)第四作者以後作者 |
| 67. | Qun Lin, Yi-Jang Lee, Zhong Yun (co-first author). Differentiation arrest by hypoxia. Journal of Biological Chemistry 2006; 28(31):30678-30683 (SCI). (Impact factor: 4.238;Rank: 29.13%)第一作者/通訊作者作者 |
| 68. | Mazzatti DJ, Lee YJ, Helt C, O’Reilly MA, Keng PC. P53 modulates radiation sensitivity independent of p21cip1. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS 2005; 28(1):43-50 (SCI). (Impact factor: 1.907;Rank: 85.86%)第二作者作者 |
| 69. | Yi-Jang Lee, Tzong-Jen Sheuand Peter C. Keng. Enhancement of radiosensitivity in H1299 cancer cells by actin-associated protein cofilin. Biochemical and Biophysical Research Communications 2005; 335(2):286-291 (SCI). (Impact factor: 2.985;Rank: 35.92%)第一作者/通訊作者作者 |
| 70. | Yi-Jang Lee, Dawn J. Mazzatti, Zhong Yun and Peter C. Keng. Inhibition of invasiveness of human lung cancer cell line H1299 by over-expression of cofilin. Cell Biology International 2005; 29(11):877-883 (SCI). (Impact factor: 2.571;Rank: 71.03%)第一作者/通訊作者作者 |
| 71. | Yi-Jang Lee and Peter C. Keng. Studying the effects of actin cytoskeletal destabilization on cell cycle by cofilin over-expression. Molecular Biotechnology 2005; 31(1):1-10 (SCI). (Impact factor: 2.022;Rank: 66.99%)第一作者/通訊作者作者 |
| 72. | Helt CE, Staversky RJ, Lee YJ, Bambara RA, Keng PC, O’Reilly MA.. The Cdk and PCNA domains on p21Cip1 both function to inhibit G1/S progression during hyperoxia. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 2004; 286(3):L506-L513 (SCI). (Impact factor: 4.418;Rank: 14.20%)第三作者作者 |
| 73. | Chen Y, Pandya K, Keng PC, Johnstone D, Li J, Lee YJ, Smudzin T, Okunieff P.. Phase I/II clinical study of pulsed paclitaxel radiosensitization for thoracic malignancy: a therapeutic approach on the basis of preclinical research of human cancer cell lines. Clinical Cancer Research 2003; 9(3):969-975 (SCI). (Impact factor: 10.107;Rank: 7.17%)第四作者以後作者 |
| 74. | Liao GJ, Lee YJ, Lee YH, Chen LL, and Chu WS. Structure and expression of the D-amino-acid oxidase gene from the yeast R toruloides. Biotechnology and Applied Biochemistry 1998; 27(1):55-61 (SCI). (Impact factor: 1.638;Rank: 79.81%)第二作者作者 |
| 75. | Lee YJ, Chen YP, Wang SH, Chow WY, and Lin LY. Structure and expression of metallothionein gene in ducks. GENE 1996; 176(12):85-92 (SCI). (Impact factor: 2.984;Rank: 46.91%)第一作者/通訊作者作者 |
(Ｂ) 專書發表
| 出版年度 | 作者 | 專書/專章名稱 | 出版社/學術專書 |
| 2021 | Chun-Yuan Chang,… Yi-Jang Lee | (978-93-90149-78-0)Highlights on Medicine and Medical Research/Correlation of cofilin-1 and Twist-1 protein expression in human lung cancer | B P International |
| 2012 | Yi-Jang Lee, Pei-Hsun Chiang, Peter C. Keng | (978-953-307-845-8)Retinoblasoma – Chapter: Cytoskeletal organization and Rb tumor suppresor gene | InTech – Open Access Publisher |
(Ｃ) 研討會發表
| 1. | Cheng−Han Tsai, Chun−Yuan Chang, Liang−Tin Lin, Yi -Jang Lee, The cofilin-TEAD1-p27Kip1 pathway ablates cell senescence,American Association for Cancer Research,亞特蘭大,2019 |
| 2. | 林秉澤, 汪珊瑩, 張志賢, 李易展, Systemic change of microRNAs in rhenium-188 liposome treated human head and neck cancer cells profiling by openarray,34屆生物醫學年會,國防醫學院,2019 |
| 3. | 林姿婷, 呂志得, 林雲蓮, 李易展, The Effect of Extract of Lophatheri Herba to Promote Wound Healing and the Application of Matlab to Quantify the Results,34屆生物醫學年會,國防醫學院,2019 |
| 4. | 吳孟修, 呂志得, 李易展, Use cofilin-1 as the biomarker for evaluating the efficacy of radiation therapy,34屆生物醫學年會,國防醫學院,2019 |
| 5. | Min-Ying Lin, Yi-Jang Lee, Multimodality molecular imaging based tracing and isolating the remnant living cells in human head and neck squamous cell carcinoma,2019 14th International Symposium on Medical Imaging and Radiology,高雄義守大學,2019 |
| 6. | Meng-Hsiu Wu, Chun-Yuan Chang, Yi-Jang Lee, Using cofilin-1 as the biomarker for evaluating the efficacy of radiation therapy,2019 14th International Symposium on Medical Imaging and Radiology,高雄義守大學,2019 |
| 7. | Bing-Ze Lin, Chun-Yuan Chang, Chih-Hsien Chang, Yi-Jang Lee, Openarray profiling of the systemic change of microRNAs in rhenium-188 liposome treated human head and neck cancer cells.,2019 American Association for Cancer Research Annual Meeting.,Georgia World Congress Center, Atlanta, Georgia, USA,2019 |
| 8. | Bing-Ze Lin, Chun-Yuan Chang, Chih-Hsien Chang, Yi-Jang Lee, Microarray Analysis for Investigating the Systematic Change of microRNAs in Rhenium-188 Liposome Treated Human Head and Neck Cancer Cells.,13th International Symposium of Medical Imaging and Radiological Science Conference. For having selected as a recipient of the Third Place of the English Oral Presentation,Chung Shan Medical University,2018 |
| 9. | Bing-Ze Lin, Jyh-Der Leu, Yuan-Heng Tu, Yun-lian Lin, Yi-Jang Lee, Ajuga taiwanensis extracts suppressed senescent phenotypes was accompanied by down-regulation of cofilin-1,2018 The 33th Joint Annual Conference of Biomedical Science,National Defense Medical Center,2018 |
| 10. | Chun-Yuan Chang, Pei-Hsun Chiang, Yi-Jang Lee, Cofilin-1 is associated with replicative origins licensing through regulation of MCM2-7 helicase,American Association for Cancer Research Annual Meeting 2018,Chicago, Illinois,2018 |
| 11. | Chun-Yuan Chang, Chao-Cheng Chen, Liang-Ting Lin,Yi-Jang Lee, Therapeutic Efficacy and potent tumor suppressive effect via microRNA profiling in repeated therapy with PEGylated liposome encapsulated Rhenium-188 in human head and neck cancer animal model,World Molecular Imaging Congress (WMIC),Seattle, USA,2018 |
| 12. | Chun-Yuan Chang, Chun-Yu Wang, Wei R. Chen, Yi-Jang Lee, EFFECTS OF GLYCATED CHITOSAN ON THE ENHANCEMENT OF RADIOSENSITIVITY IN MURINE BREAST CANCER CELLS,33屆生物醫學年會,國防醫學院,2018 |
| 13. | Chun-Yuan Chang, Chao-Cheng Chen, Liang-Ting Lin,Chih-Hsien Chang, Hsin-Ell Wang, Ren-Shyan Liu, Te-Wei Lee, Yi-Jang Lee, Assessment of Repeated Therapy with PEGylated Liposome Encapsulated 188Re in Human Head and Neck Cancer preclinical model,學術論文研討會,陽明大學,2018 |
| 14. | Chun−Yuan Chang, Jyh-Der Leu, Yi -Jang Lee, Cofilin-1 is associated with replicative origins licensing through regulation of MCM2-7 helicase,American Association for Cancer Research,芝加哥,2018 |
| 15. | Chun-Yu Wang, Chung-Yih Wang, Chun-Yuan Chang, Wei R. Chen, Yi-Jang Lee, Effects of glycated chitosan on the enhancement of radiosensitivity of cancer stem cells derived from murine breast adenocarcinoma,SPIE Photonics West Exhibition,San Fransico,2017 |
| 16. | Arthur Wang, Chuang-Yun Chang, Wei R, Chen, Yi-Jang Lee, Effects of glycated chitosan on the enhancement of radiosensitivity of cancer stem cells derived from murine breast adenocarcinoma (Control ID: 2759269 ),World Molecular Imaging Congress,美國費城,2017 |
| 17. | Chun-Yuan Chang, Chao-Cheng Chen, Yi-Jang Lee, Double injections of Rhenium-188 liposomal drug could cause a defect in tumor growth through regulating the expressions of EMT related markers in HNSCC tumor-bearing mouse model,World Molecular Imaging Congress 2017,Philadelphia Convention Center, PA,2017 |
| 18. | Chun-Yu Wang, Chun-Yuan Chang, Yi-Jang Lee, Low dose radiation promoted unirradiated tumor migration is associated with c-Myc mediated bystander effects,World Molecular Imaging Congress,紐約,2016 |
| 19. | Chun-Yuan Chang, Lo-Chia Chien, Bo-Shen Wang, Yi-Jang Lee, Unirradiated tumor migration via low dose radiation is related to c-Myc mediated bystander effects,Joint meeting of the 11th symposium of medical imaging and radiological science 2016 Taipei International Symposium of Molecular Imaging and 2016 TSMI Annual Meeting,陽明大學活動中心,2016 |
| 20. | 杜元亨,蔡政翰,呂志得,林雲蓮,李易展, 切絲蛋白參與散血草調控之延遲老化作用,第二十一屆台灣癌症聯合學術年會,台大國際會議中心,2016 |
| 21. | Chun-Yuan Chang, Wei-Kang Kwang,Tien-Heng Huang, Chung-Yih Wang, Yi-Jang Lee, The role of Rho signaling pathway on the hypoxia mediated suppression of adipogenesis,第31屆生物醫學聯合學術年會,國防醫學院,2016 |
| 22. | Chun-Yuan Chang, Chi-Hsien Chang, Hsin-Ell Wang, Te-Wei Lee3, Yi-Jang Lee, The study of using Rhenium-188 liposomal drug and 5-FU in chemoradiotherapy to suppress tumor growth in head and neck squamous cancer,SNMMI 2016 Annual Meeting,聖地牙哥,2016 |
| 23. | Yuan-Heng Tu ,Yun-Lian Lin,Yi-Jang Lee, ADF/Cofilin-1 is involved in a senescence delaying effect caused by a traditional Chinese medicine,第三十一屆生物醫學聯合學術年會,國防醫學院,2016 |
| 24. | Yuan-HENG Tu, Chung-Yih Wang, Chun-Yuan Chang, Chun-yu Wang, Yi-Jang Lee, Effects of glycated chitosan on the enhancement of radisensitivity of cancer stem cells derived from murine breast adenocarcinoma, 2016 Kyoto Breast Cancer Consensus,京都市,2016 |
| 25. | Hsin-Yu Chiu1,Jyh-Der Leu2, Wei R. Chen3, Yi-Jang Lee1, The synergistic effects of radiofrequency ablation (RFA) with glycated chitosan for inhibiting the metastasis of breast cancer,SPIE Photonics West 2016,舊金山,2016 |
| 26. | Hsin-Yu Chiu1,Jyh-Der Leu2, Wei R. Chen3, Yi-Jang Lee1, The synergistic effects of radiofrequency ablation (RFA) with glycated chitosan for inhibiting the metastasis of breast cancer,第三十一屆生物醫學聯合學術年會,國防醫學院,2016 |
| 27. | Hsin-Yu Chiu1,Jyh-Der Leu2, Wei R. Chen3, Yi-Jang Lee1, The synergistic effects of radiofrequency ablation (RFA) with glycated chitosan for inhibiting the metastasis of breast cancer,第二十一屆台灣癌症聯合學術年會,台灣大學,2016 |
| 28. | Cheng-Han Tsai, Liang-Ting Lin, Chung-Yih Wang, Yu-Wen Chiua, Yen-Ting Choua, Shu-Jun Chiug, Hsin-Ell Wang, Ren-Shyan Liu, Chun-Yi Wua, Pei-Chia Chan, Muh-Hwa Yang, Shih-Hwa Chiou, Man-Jyun Liao, Yi-Jang Lee, Over-expressed cofilin-1 displayed suppressive role on tumorigenesis of a lung cancer cell line,第三屆基因暨藥物基因大會(3rd Genomics & Pharmacogenomics),美國聖安東尼奧希爾頓飯店 (Hilton San Antonio airport, TX, U.S.A.),2015 |
| 29. | Hsin-Yu,Chiu1,Jyh-Der Leu2, Wei R. Chen3, Yi-Jang Lee1, The synergistic effects of radiofrequency ablation (RFA) with glycated chitosan (GC) for inhibiting the metastasis of breast cancer.,台灣分子生物影像學會,陽明大學,2015 |
| 30. | Chang, Chun-Yuan1*;Lin, Liang-Ting1; Chang, Chih-Hsien2; Wang, Hsin-Ell1; Liu, Ren-Shyan1; Lee, Te-Wei2; Lee, Yi-Jang1, Study of Tumor Suppressive Response of microRNA let-7i in Rhenium-188 Liposomal Drug Treated Head and Neck Squamous Cell Cancer,世界分子影像大會,檀香山會議中心,2015 |
| 31. | Chun-Yuan Chang1*, Liang-Ting Lin1, Yuan-Heng Tu1, Chih-Hsien Chang2, Hsin-Ell Wang1 , Ren-Shyan Liu1,4, Te-Wei Lee2,Yi-Jang Lee1,3, Rhenium-188 liposomal drug increases therapeutic efficacy through triggering of microRNA let7i expression in head and neck squamous cancer,TSMI（台灣分子生物影像大會）,國立陽明大學活動中心,2015 |
| 32. | Chun-Yuan Chang, Jyh-Der Leu, Chung-Yih Wang, Yi-Jang Lee, The Combination of radiotherapy and immunotherapy using glycated chitosan as an immunological stimultant,SPIE Photonics West 2015,加州舊金山,2015 |
| 33. | 林亮廷、李易展, Tumor suppressive profiling of nanopegylated Rhenium-188 liposomal drug treating head and neck squamous cell cancer,SNMMI 2014 Annual Meeting,St. Louis Convention Center, St. Louis, MO,2014 |
| 34. | Chia-Chien Lo, Jyh-Der Leu, Yi-Syuan Chen, Wen-Hsin Hung, Jeng-Jong Hwang, Yi-Jang Lee, Low dose radiation mediated upregulation c-Myc oncogene and cofilin1 induced cellular senescence phenomenon and indirectly affected unirradiated cells metastasis ability, P558,World Molecular Imaging Congress,首爾,2014 |
| 35. | Yi-Jang Lee, Yi-Ling Chen, Chung-Yih Wang, Fang-Yi Yang, Bo-Sheng Wang, Liang-Ting Lin, Jyh-Der Leu, and Wei R. Chen, Imaging the synergistic effects of the immunoadjuvant glycated chitosan with high-intensity focused ultrasound on suppression of metastases in a syngeneic breast tumor model,World Molecular Imaging Congress,首爾,2014 |
| 36. | Liang-Ting Lin, Mun-Jun Liao, Te-Wei Lee, Yi-Jang Lee, Tumor Suppressive Profiling of Rhenium-188 Liposomal Drug Treated Head and Neck Squamous Cancer Cells, P110,World Molecular Imaging Congress,首爾,2014 |
| 37. | 廖曼均, 蔡政翰, 李易展, 利用非入侵分子影像探討微型RNA let7家族對腫瘤入侵轉移能力的影響, P7,103年度振興醫院院慶,台北,2014 |
| 38. | Liang-Ting Lin, Shih-Hwa Chiou, Yi-Jang Lee, Study of the tumor suppressive machinery of arsenic trioxide-induced glioblastoma multiforme inhibition via microRNA-182-Sestrin2 regulatory circuit,2014 Annual Meeting of American Association for Cancer Research,San Diego, CA,2014 |
| 39. | Liang-Ting Lin*, Jyh-Der Leu*, Shih-Hwa Chiou, Yi-Jang Lee, Study of the tumor suppressive machinery of arsenic trioxide-induced glioblastoma multiforme inhibition via microRNA-182-Sestrin2 regulatory circuit,AACR,加州聖地牙哥,2014 |
| 40. | 羅佳茜、林詩婷、周彥廷、蔡政翰、李易展, c-Myc induced senescence is dependent on transactivation of actin depolymerizing factor (ADF)/cofilin to mediate potent bystander effect,AACR,加州聖地牙哥,2014 |
| 41. | Liang-Ting Lin, Jyh-Der Leu, Shih-Hwa Chiou, Yi-Jang Lee, Study of the tumor suppressive machinery of arsenic trioxide-induced glioblastoma multiforme inhibition via microRNA-182-Sestrin2 regulatory circuit,AACR,加州聖地牙哥,2014 |
| 42. | Lin, Liang-Ting1; Chang, Chih-Hsien1; Yu, Hsiang-Lin; Tang, Jo-Hsin, Wang, Hsin-Ell1; Liu, Ren-Shyan; Lee, Te-Wei; Lee, Yi-Jang, Therapeutic Efficacy and Tumor Suppressive Profiling of Rhenium-188-liposome Treated Head and Neck Squamous Cell Cancer,TSMI,台北晶華酒店,2014 |
| 43. | Cheng-Han Tsai1, Chi-Chao Liu1, Liang-Ting Lin1, Yen-Ting Chou1, Ren-Shyan Liu1,2,3, Chung-Yi Wu1, Pei-Chia Chan1, Hsin-Ell Wang1, Muh-Hwa Yang4 and Yi-Jang Lee1,5*, ENFORCED EXPRESSION OF COFILIN-1 SUPPRESSES EARLY GROWTH OF HUMAN NON-SMALL CELL LUNG CANCER ACCOMPANIED BY UP-REGULATION OF TUMOR SUPPRESSIVE MICRORNA LET-7 FAMILY,Conference of the Federation of Asain Societies for Molecular Imaging,台北榮總致德樓,2013 |
| 44. | Ying-Ling Chen, Wei R. Chen, Ren-Shyan Liu, Feng-Yi Yang, Chung-Yi Wang, Yi-Jang Lee, Using immunoadjuvant agent glycated chitosan to enhance anti-tumor immunity induced by HIFU,Photonics West 2013,舊金山,2013 |
| 45. | Chia-Chien Lo, Wen-Hsin Hung, Jyh-Der Leu, Ran-Chou Chen, Jeng-Jong Hwang, Yi-Jang Lee, Low dose radiation mediated upregulation c-myc induced cellular senescence phenomenon and metastasis bystander effect,2013第八屆醫學影像暨放射科學研討會,元培科技大學,2013 |
| 46. | Lin, Liang-Ting; Chang, Chih-Hsien; Lee, Te-Wei; Lee, Yi-Jang, Tumor suppressive profiling in Rhenium-188 embedded PEGylated liposome treated NSCLC animal model,2013 Annual Meeting of SNMMI,Vancouver,2013 |
| 47. | 蔡政1, 林亮廷, 楊慕華, 劉仁賢, 李易展, 利用非侵入式造影觀察let7i對於抑制人類腫瘤轉移之情形,第二十八屆生物醫學聯合學術年會,國防醫學院,2013 |
| 48. | Cheng-Han Tsai, Jeng-Jong Hwang, Ren-Shyen Liu, Muh-Hwa Yang and Yi-Jang Lee, Investigation of the cellular senescence induced by ADF/cofilin-YAP-p27kip1 regulator pathway,國立陽明大學校內學術論文研討會,國立陽明大學,2013 |
| 49. | Liang-Ting Lin, Bo-Sheng Wang, Jyh-Cheng Chen, Chi-Hsien Liu, Chien Chou, Shu-Jun Chiu, Wen-Yi Chang, Ren-Shyan Liu , C. Allen Chang, Yi-Jang Lee, The mPlum-IFP 1.4 fluorescent fusion protein displays Förster resonance energy transfer (FRET)-like properties that can be used for near-infrared based reporter gene imaging,World Molecular Imaging Congress,美國喬治亞鎮,2013 |
| 50. | 羅佳茜, 呂志得, 洪文欣, 李易展*, 呂志得, 低劑量游離輻射調控cMyc和cofilin細胞切絲蛋白表現造成細胞老化及間接影響周邊細胞轉移能力的現象,第十八屆台灣癌症聯合學術年會,台北,2013 |
| 51. | Cheng-Han Tsai, Muh-Hwa Yang, Liang-Ting Lin, Yi-Jang Lee, ENFORCED EXPRESSION OF COFILIN-1 SUPPRESSES EARLY GROWTH OF HUMAN NON-SMALL CELL LUNG CANCER ACCOMPANIED BY UP-REGULATION OF TUMOR SUPPRESSIVE MICRORNA LET-7 FAMILY (1-5),2013 Conference of the Federation of Asian Societies for Molecular Imaging,Taipei,2013 |
| 52. | Liang-Ting Lin, Chih-Hsien Chang, Hsiang-Lin Yu, Te-Wei Lee, Yi-Jang Lee, Therapeutic efficacy and tumor suppressive profiling of Rhenium-188 liposomal drug treating head and neck squamous cell cancer (3-10),2013 Conference of Federation of Asian Societies for Molecular Imaging,Taipei,2013 |
| 53. | Yi-Jang Lee, Cheng-Han Chao, Ying-Feng Chang, Chien Chou, Assessments of urine cofilin-1 in patients hospitalized in the intensive care units with acute kidney injury,2013 Photonics West,舊金山,2013 |
| 54. | Bo-Sheng Wang, Yi-Jang Lee, Jyh-Der Leu, Combination of flavonoid fiestin and ionizing radiation on treatment of the colorectal cancer-bearing animal model (3-11),2013 Conference of the Federation of Asian Societies for Molecular Imaging,Taipei,2013 |
| 55. | Cheng-Han Tsai1, Jeng-Jong Hwang1, Ren-Shyen Liu1, Muh-Hwa Yang2 and Yi-Jang Lee1,*, Investigation of the cellular senescence induced by ADF/cofilin-YAP-p27kip1 regulator pathway,國立陽明大學校內學術論文研討會,國立陽明大學,2012 |
| 56. | Cheng-Han Tsai1, Liang-Ting Lin1, Muh-Hwa Yang2, 3, Ren-Shyan Liu3, 4, Yi-Jang Lee1, *, 利用多模組分子造影探討微型核醣核酸let7i在動物體內調控人類 頭頸癌侵犯與復發之情形,2012世界分子影像研討會,都柏林,2012 |
| 57. | Cheng-Han Tsai, J.J. Hwang, Yen-Ting Chou, R. S. Liu and Yi-Jang Lee, Morphological transformation and Actin Depolymerization Regulated by ADF/cofilin are Essential in Driving Cellular Senescence,2012生物醫學聯合學術年會,國防醫學院,2012 |
| 58. | Yu-Wen Chiu, Jyh-Der Leu, Ran-Chou Chen, Yi-Jang Lee, Latrunculin-A Induce Actin Cytoskeleton Disruption Increasing Actin-Associated Protein Cofilin Phosphorylation would Enhance Radiosensitivity,第27屆生物醫學聯合學術年會,國防醫學院,2012 |
| 59. | Liang-Ting Lin, Shih-Hwa Chiou, Hsin-Ell Wang, Ran-Shyan Liu, Hsin-I Ma, Yi-Jang Lee, Study of Glioblastoma Multiforme Metastatic and Invasive Mechanism by Polycistronic Imaging Probe in Orthotopic Implanted Animal Model,2011 Society of Nuclear Medicine Anual Meeting,San Antonio, TX,2011 |
| 60. | Liang-Ting Lin*, Shih-Hwa Chiou, Chiung-Tung Chen, Hsin-I Me, Yi-Jang Lee, Study of Glioblastoma Multiforme Metastatic and Invasive Mechanism by Polycistronic Imaging Probe in Orthotopic Implanted Animal Model,The 26th Joint Annual Conference of Biomedical Science,國防醫學院,2011 |
| 61. | Cheng-Han Tsai, Yen-Ting Chou, Yi-Jang Lee*, Cofilin mediates actin destabilization and shape change in replicative senescence and stress-induced premature senescence,第26屆生物醫學聯合學術年會,國防醫學院,2011 |
| 62. | Yen-Ting Chou, Chien-Hsien Chen, Yi-Jang Lee*, Actin depolymerizing factor (ADF)/Cofilin intermediates cellular senescence induced by over-expressed c-myc,第26屆生物醫學聯合學術年會,國防醫學院,2011 |
| 63. | Shiau-Yi Wang, Hsin-Ell Wang, Jyh-Cheng Chen, Ren-Shyan Liu, Jeng-Jong Hwang and Yi-Jang Lee*, Application of non-viral gene delivery system, piggyBac, in molecular imaging on murine breast cancer model,第26屆生物醫學聯合學術年會 ,國防醫學大學,2011 |
| 64. | Cheng-Han Tsai, Cofilin Mediates Actin Destabilization and Shape Change in Replicative Senescence and Stress-Induced Premature Senescence,校內學術論文研討會,國立陽明大學,2011 |
| 65. | Cheng-Han Tsai, Yan-Ting Chou and Yi-Jang Lee*, Cofilin mediates actin destabilization and shape change in replicative senescence and stress-induced premature senescence,102 AACR Annual Meeting,美國奧蘭多,2011 |
| 66. | Cheng-Han Tsai and Yi-Jang Lee, Cofilin mediates actin destabilization and shape change in replicative senescence and stress-induced premature senescence,2011 International Symposium on Frontier Biomedical and Molecular Imaging,台北榮總,2011 |
| 67. | Shiau-Yi Wang, Jeng-Jong Hwang, Yi-Jang Lee., Inhibition of cancer cell invasiveness by over-expressed cofilin, an actin binding protein, is associated with down-regulation of the matrix metalloproteases,2010第15屆台灣癌症學術年會,台北榮民總醫院,2010 |
| 68. | Liang-Ting Lin, Shih-Hwa Chiou, Yi-Jang Lee, Study of glioblastoma stem cell-like cancer stem cells on tumorigenesis and recurrence by multiple imaging modalities,101st American Association Cancer Research Annual Meeting,Washington, DC, USA,2010 |
| 69. | Pei-Hsun Chiang, Shih-Chieh Hung, Yi-Jang Lee, The expression and activity of actin-regulating protein cofilin are associated with the cell cycle progression,American Association Cancer Research,美國華盛頓特區,2010 |
| 70. | Han-Yi Tsai, Yi-Jang Lee, M.D., Ph.D., Dr. Jyh-Der Leu, An association of MDM2 SNP 309, MDM2 SNP354 and p53 Codon R72P with the incidence of breast cancer in Taiwan,OOTR the 6th Annual Conference,Kyoto, Japan,2010 |
| 71. | Yen-Ting Chou, Cheng-Han Tsai, Yuan-Hao Lee, Yi-Jang Lee, Induction of the senescence phenomenon by forced expression of actin depolymerizing factor (ADF)/cofilin in the absence of p53 and p16INK4,第25屆生物醫學聯合學術年會,國防醫學大學,2010 |
| 72. | Pei-Hsun Chiang,Jeng-Jong Hwang ,Yi-Jang Lee, Association of actin-regulation protein cofilin on cell cycle progression and radiosensitivity in human lung cancer cells,第十五屆台灣癌症聯合學術年會,台北榮民總醫院,2010 |
| 73. | Pei-Hsun Chiang, Yi-Jang Lee, The expression and activity of actin-regulating protein cofilin are associated with the cell cycle progression,國防生醫年會,國防醫學院,2010 |
| 74. | Yen-Ting Chou, Cheng-Han Tsai, Yuan-Hao Lee, Yi-Jang Lee, Induction of the senescence phenomenon by forced expression of actin depolymerizing factor (ADF)/cofilin in the absence of p53 and p16INK4,2010第15屆台灣癌症學術年會,台北榮民總醫院,2010 |
| 75. | Liang-Ting Lin, Shih-Hwa Chiou, Yi-Jang Lee, Study of glioblastoma stem cell-like cancer stem cells on tumorigenesis and recurrence by multiple imaging modalities,The 15th Taiwan Joint Cancer Conference,Taipei,2010 |
| 76. | S.Y. Wang, Y.J. Lee, Use of the piggyBac Transposon Based Gene Delivery System for Dual Reporter Gene Imaging,第25屆生物醫學聯合學術年會,國防醫學大學,2010 |
| 77. | Liang-Ting Lin, Shih-Hwa Chiou, Yi-Jang Lee, Study of glioblastoma stem cell-like cancer stem cells on tumorigenesis and recurrence by multiple imaging modalities,The 25th Joint Annual Conference of Biomedical Science,Taipei, Taiwan,2010 |
| 78. | Liang-Ting Lin, Shih-Hwa Chiou, Yi-Jang Lee, Study of glioblastoma stem cell-like cancer stem cells on tumorigenesis and recurrence by multiple imaging modalities,2010 World Molecular Imaging Congress,Kyoto, Japan,2010 |
| 79. | Han-Yi Tsai, Yi-Jang Lee, The Relationship Between Single Nucleotide Polymorphism MDM2 SNP 309, P53 Codon R72P and the Risk of Breast Cancer,Symposium of Bioinformaties and Systems Biology in Taiwan,National YangMing University,2009 |
| 80. | Liang-Ting Lin, Yi-Jang Lee, Use of foamyviral gene delivery system for reporter genes of optical imaging in vitro,The 3rd International Symposium on Bio-Inspired Engineering,Academia Sinica, Taipei, Taiwan,2009 |
| 81. | Cheng-Han Tsai, Jeong-Jong Hwang, Ren-Shen Liu, Yi-Jang Lee*, Study of actin depolymerizing factor (ADF)/cofilin on tumorigenesis by multi-modality reporter gene imaging. Abstract No. 4001,AACR Annual Meeting,Colorado, USA,2009 |
| 82. | C.-H. Tsai, J.J. Hwang, H.E. Wang, R.S. Liu, Y.-J. Lee, Multi-modality imaging of the effects of actin depolymerizing factor (ADF)/cofilin on tumorigenesis using a small animal (Oral),14th World Congress on Advances in Oncology and 12th International Symposium on Molecular Medicine,Greece,2009 |
| 83. | Liang-Ting Lin and Yi-Jang Lee, Use of fomayviral gene delivery system as a novel molecular imaging system,World Molecular Imaging Conference,加拿大,2009 |
| 84. | Shiau-Yi Wang and Yi-Jang Lee, Use of the piggyBac Transposon Based Gene Delivery System for Dual Reporter Gene Imaging,2009台灣分子生物影像學會年會暨學術研討會,台北國立陽明大學,2009 |
| 85. | 蔡政翰 李易展, Use Multi-modality Reporter Gene Imaging Monitoring Tumorigenesis Inhibition Mediated by ADF/Cofilin,2009台灣分子生物影像學會年會暨學術研討會,台灣台北,2009 |
| 86. | Liang-Ting Lin, Yi-Jang Lee, Use of foamyviral gene delivery system for reporter genes of optical imaging in vitro,6th Taipei International Symposium for Molecular Imaging,Taipei,2009 |
| 87. | 蔡政翰, 黃正仲, 劉仁賢, 李易展, Study of actin depolymerizing factor (ADF)/cofilin on tumorigenesis by multi-modality reporter gene imaging.,2008第四屆國際醫學影像暨放射科學研討會,台灣高雄,2008 |
| 88. | 蔡政翰, 黃正仲, 劉仁賢, 李易展, Study of actin depolymerizing factor (ADF)/cofilin on tumorigenesis by multi-modality reporter gene imaging.,2008第二屆國際分子影像研討會,台灣台中,2008 |
| 89. | Cheng-Han Tsai, Jyh-Der Leu, John J.J. Hwang , Yuan-Hao Lee,Yi-Jang Lee, Over-expression of actin depolymerization factor (ADF)/cofilin leads to increase of radiosensitivity in human lung cancer cell.,第13 屆癌症醫學年會,台北國防醫學院,2008 |
| 90. | Yuan-Hao Lee, Jyh-Der Leu , Chih-Chao Liu, Cheng-Han Tsai, John J.J. Hwang, Yi-Jang Lee, Actin Depolymerizing Factor (ADF) Cofilin Induced G1-Phase Arrest Is Associated with p27kip1 Up-regulation.,第13 屆癌症醫學年會,台北國防醫學院,2008 |
| 91. | Yi-Jang Lee, John J.J. Hwang, Cheng-Han Tsai, Yuan-Hao Lee, Imaging of actin depolymerizing factor (ADF)/cofilin over-expression on tumor control by Bioluminescence,2008 SNM Annual Meeting,紐奧良, 美國,2008 |
| 92. | Yi-Jang Lee (Oral), Non-invasive reporter gene imaging for determining the inhibition kinetics of tumorigenesis by actin depolymerizing factor (ADF)/cofilin.,2008 World Molecular Imaging Conference,尼斯, 法國,2008 |
| 93. | Chih-Chao Liu, Yuan-Hao Lee, Cheng-Han Tsai, Wushou P. Chang , John J.J. Hwang, Yi-Jang Lee, Actin Depolymerizing Factor/ Cofilin Induced Radiosensitivity Is Dependent on G1 Phase Arrest.,2007 第三屆國際醫學影像暨放射科學研討會,,台中中山醫學大學,2007 |
| 94. | Ying- Fang Sun, Jyh-Der Leu, Su-Mei Chen, and Yi-Jang Lee, Study of the association between cancerous onset and MDM2 SNP309 in Taiwanese population,2007 Symposium of Bioinformatics and System Biology in Taiwan,ChiaYi,2007 |
| 95. | 劉智超、黃正仲、張武修、李易展*, A potential effect of cofilin on mediating cellular responses to ionizing radiation,AACR Annual Meeting 2007,洛杉磯,2007 |
| 96. | Chih-Chao Liu, Jeng-Jong Hwang and Yi-Jang Lee, Expression of Orphan Receptor TR2 in A549 after Ionizing Irradiation, A5,2006 第二屆生醫影像暨放射科學學術研討會,陽明大學,2006 |
| 97. | Yi-Jang Lee and Peter Keng, Enhancement of radiation sensitivity by destabilization of actin cytoskeleton in human lung cancer cell line,Cancer Center Symposium,Rochester, USA,2002 |
| 98. | Mazzatti D, Yi-Jang Lee and Peter Keng, Decrease of DNA repair activity by restoration of p53 status in H1299 cells,Poster Session of Dept. of Pathology,Rochester, USA,2002 |
| 99. | Yi-Jang Lee and Peter Keng, Overexpression of actin deploymerization factor (ADF)/cofilin up-regulates p21WAF1/CIP1 in H1299 cells,Cancer Center Symposium,Rochester, USA,2001 |
| 100. | Yi-Jang Lee, Peter Keng and Chawnshang Chang, Inhibition of orphan receptor TR2 expression by p53 after ionizing irradiation,International Radiation Society,New Mexico, USA,2000 |
| 101. | Chang, Chun-Yuan1*;Lin, Liang-Ting1; Chang, Chih-Hsien2; Wang, Hsin-Ell1; Liu, Ren-Shyan1; Lee, Te-Wei2; Lee, Yi-Jang1, Study of Tumor Suppressive Response of microRNA let-7i in Rhenium-188 Liposomal Drug Treated Head and Neck Squamous Cell Cancer,2015 World Molecular Imaging Congress,Hawaii convention center,104 |
| 102. | Chang, Chun-Yuan1*;Lin, Liang-Ting1; Chang, Chih-Hsien2; Wang, Hsin-Ell1; Liu, Ren-Shyan1; Lee, Te-Wei2; Lee, Yi-Jang1, Study of Tumor Suppressive Response of microRNA let-7i in Rhenium-188 Liposomal Drug Treated Head and Neck Squamous Cell Cancer,2015 World Molecular Imaging Congress,Hawaii convention center,104 |
| 103. | Chang, Chun-Yuan1*;Lin, Liang-Ting1; Chang, Chih-Hsien2; Wang, Hsin-Ell1; Liu, Ren-Shyan1; Lee, Te-Wei2; Lee, Yi-Jang1, Study of Tumor Suppressive Response of microRNA let-7i in Rhenium-188 Liposomal Drug Treated Head and Neck Squamous Cell Cancer,2015 World Molecular Imaging Congress,Hawaii convention center,104 |
研究成果智慧財產權
(A) 專利
| 專利名稱 | 專利國別 | 國內/外 | 發明人 | 專利權人 | 專利期間期間 |
| 一種處理細胞老化的方法 | 中華民國 | 國內 | 李易展、林雲蓮、黃重生、蔡政翰、張淳湲、林秉澤、 杜元亨、許偉祥、 羅品荷 | 國立陽明大學 | 2021/05/01至2040/05/21 |
| 螢光融合蛋白 | 中華民國 | 國內 | 李易展、 王柏勝、 林亮廷、 張正、 陳志成 | 國立陽明大學 | 2014/06/13至2034/06/12 |
| Methods for In vivo Identification of Cancer Initiating Cells by Multimodality Reporter Gene Imaging | 美國 | 國外 | 王孝頤、李易展 | 國立陽明大學 | 2012/06/15至2032/06/14 |
| 一種評估細胞老化的方法 | 中華民國 | 國內 | 李易展, 蔡政翰 | 國立陽明大學 | 2011/08/25至2031/08/25 |
| Method for evaluating cell aging by expression level of cofilin | 美國 | 國外 | 李易展, 蔡政翰 | 國立陽明大學 | 2011/07/01至2031/06/30 |
| Method for treatment of cellular senescence | 美國 | 國外 | 李易展、林雲蓮、黃重生、蔡政翰、張淳湲、林秉澤、 杜元亨、許偉祥、 羅品荷 | MOST 105-2628-B-010-013-MY3 | |
| FLUORESCENT FUSION PROTEIN | 美國 | 國外 | 王柏勝、林亮廷、張正、陳志成、李易展 | 國立陽明大學 | |
| Kit for preparation of target radiopharmaceuticals and method of using it | 美國 | 國外 | 邱淑珮、林伯憲 、林亮廷、李易展、李德偉、黃蜂運、羅建苗 | 核能研究所 |
(B) 技術授權
| 技術名稱 | 授權單位 | 被授權單位 | 合約期間 | 權益金(元) |
| 一種處理老化細胞的方法 | 國立陽明大學 | 安益藥業股份有限公司 | 2020/05/21至2030/05/20 | 0 |
研究計畫
| 年度 | 計畫名稱 | 類型 | 計畫內擔任之工作 | 執行期間 | 經費提供單位 | 執行經費(元) |
| 2021 | 建立人類原位肺癌小動物模式以探討鎦-177標定之上皮生長因子核醫藥物之診療效果 | 主持人 | 2021/01/01~2021/12/31 | 榮總台灣聯合大學合作研究計畫 | 305000 | |
| 2021 | 開發用於頭頸癌硼中子捕獲治療之環狀RGD胜?修飾含硼奈米金微粒 | 主持人 | 2021/01/01~2021/12/31 | 科技部 | 633000 | |
| 2021 | 以基因轉殖動物模式探討切絲蛋白對全身性輻射特性及DNA傷害反應的影響(2/3) | 主持人 | 2021/08/01~2023/07/31 | 科技部 | 1140000 | |
| 2021 | 探討人類頭頸癌餘生細胞之癌症起源細胞特性及其輻射治療反應 | 主持人 | 2021/01/01~2021/12/31 | 振陽計畫 | 527000 | |
| 2021 | 利用正子斷層掃描探討微核糖體-182對體內頭頸癌腫瘤模式發展的影響 | 主持人 | 2021/01/01~2021/12/31 | 亞陽計畫 | 148000 | |
| 2020 | 錸-188-微脂體奈米核醫藥物對頭頸癌人源化腫瘤異種接殖模式之積聚與療效探討 | 主持人 | 2020/01/01~2020/12/31 | 亞陽計畫 | 232476 | |
| 2020 | 以基因轉殖動物模式探討切絲蛋白對全身性輻射特性及DNA傷害反應的影響(1/3) | 主持人 | 2020/08/01~2023/07/31 | 科技部 | 1140000 | |
| 2019 | 切絲蛋白調控DNA預複製複合物進而影響DNA合成、修補及輻射敏感度之機制探討 | 主持人 | 2019/08/01~2020/07/31 | 科技部 | 860000 | |
| 2019 | 利用多模組分子影像技術追蹤腫瘤餘生細胞之癌症幹細胞特性 | 主持人 | 2019/01/01~2019/12/31 | 振陽計畫 | 300300 | |
| 2019 | 探討微核醣核酸miR-182於錸-188-微脂體奈米核醫藥物處理原位頭頸癌腫瘤誘發之抗氧化效應 | 主持人 | 2019/01/01~2019/12/31 | 亞陽計畫 | 360000 | |
| 2018 | 利用CRISPR-Cas9系統剔除切絲蛋白以探討老化細胞及癌細胞之反應並以電腦輔助分子模擬配合分子影像方法篩選以切絲蛋白為目標的抗老化及抗癌藥物(3/3) | 主持人 | 2018/08/01~2019/07/31 | 科技部 | 1210000 | |
| 2018 | 探討錸-188-微脂體奈米核醫藥物於原位頭頸癌腫瘤誘發之基因表現與療效評估 | 主持人 | 2018/01/01~2018/12/31 | 亞陽計畫 | 405000 | |
| 2017 | 利用微陣列基因分析錸-188-微脂體奈米核醫藥物處理原位頭頸癌腫瘤模 | 主持人 | 2017/01/01~2017/12/31 | 科技部 | 1088000 | |
| 2017 | 105/106年度臺英(MOST-RS)合作研究人員交流計畫第2年-利用多重正子造影用之核種進行體內乳癌幹細胞生長之追蹤 (2/2)(2/2) | 主持人 | 2017/03/01~2018/02/28 | 科技部 | 109000 | |
| 2017 | 利用CRISPR-Cas9系統剔除切絲蛋白以探討老化細胞及癌細胞之反應並以電腦輔助分子模擬配合分子影像方法篩選以切絲蛋白為目標的抗老化及抗癌藥物(2/3) | 主持人 | 2017/08/01~2019/07/31 | 科技部 | 1185000 | |
| 2016 | 生物醫學影像寄放射學係李易展教授105/106年部與英國皇家學院(MOST-RS)合作研究人員交流計畫案 | 個人 | 主持人 | 2016/03/01~2017/02/28 | 科技部 | 191000 |
| 2016 | 探討切絲蛋白與Twist 及 Snail轉錄因子調控途徑影響腫瘤上皮間質轉化之機制 | 其他 | 主持人 | 2016/01/01~2016/12/31 | 捐贈款項 | 330000 |
| 2016 | 利用CRISPR-Cas9系統剔除切絲蛋白以探討老化細胞及癌細胞之反應並以電腦輔助分子模擬配合分子影像方法篩選以切絲蛋白為目標的抗老化及抗癌藥物(1/3) | 主持人 | 2016/08/01~2019/07/31 | 科技部 | 1150000 | |
| 2016 | 多劑量錸-188-微脂體奈米核醫藥物合併化療藥物對人類頭頸癌及攝護腺癌小鼠模式之療效評估 | 主持人 | 2016/01/01~2016/12/31 | 科技部 | 1060000 | |
| 2016 | 探討切絲蛋白與Twist 及 Snail轉錄因子調控途徑影響腫瘤上皮間質轉化之機制 | 主持人 | 2016/01/01~2016/12/31 | 振陽計畫 | 330000 | |
| 2015 | 醣化幾丁質增加乳腺癌幹細胞輻射敏感度的效應探討 | 主持人 | 2015/01/01~2015/12/31 | 振陽計畫 | 359820 | |
| 2015 | 醣化幾丁質增加乳腺癌幹細胞輻射敏感度的效應探討 | 整合 | 主持人 | 2015/01/01~2015/12/31 | 捐贈款項 | 359820 |
| 2015 | 探討使用奈米核醫藥物錸-188-微脂體多次劑量治療人類非小細胞肺癌及頭頸癌原位小鼠模式之藥理研究 | 主持人 | 2015/01/01~2015/12/31 | 科技部 | 1100000 | |
| 2015 | c-myc訊息傳導途徑與DNA損傷修補能力對低劑量游離輻射誘發之腫瘤細胞老化與旁觀者效應的影響(3/3) | 主持人 | 2015/08/01~2016/07/31 | 科技部 | 1000000 | |
| 2014 | 多模組分子影像評估錸-188-微脂體結合化療藥物於轉移性肺癌及頭頸癌之療效 | 主持人 | 2014/01/01~2014/12/31 | 科技部 | 1049000 | |
| 2014 | 探討Lin28/let7訊息路徑於切絲蛋白大量表現後引起的細胞骨架失穩並導致腫瘤生長抑制之角色 | 主持人 | 2014/01/01~2014/12/31 | 嚴慶齡醫學研究中心 | 300000 | |
| 2014 | c-myc訊息傳導途徑與DNA損傷修補能力對低劑量游離輻射誘發之腫瘤細胞老化與旁觀者效應的影響(2/3) | 主持人 | 2014/08/01~2016/07/31 | 科技部 | 1000000 | |
| 2014 | c-myc訊息傳導途徑與DNA損傷修補能力對低劑量游離輻射誘發之腫瘤細胞老化與旁觀者效應的影響 | 個人 | 主持人 | 2013/08/01~2016/07/31 | 國科會 | 3000000 |
| 2014 | 利用非入侵分子影像探討微型RNA let7家族對腫瘤入侵轉移能力的影響 | 主持人 | 2014/01/01~2014/12/31 | 振陽計畫 | 300000 | |
| 2013 | 探討吲哚類雜環化合物增加肺癌細胞之輻射敏感度的分子機制 | 個人 | 主持人 | 2013/01/01~2013/12/31 | 國科會 | 398080 |
| 2013 | 應用多模組分子影像於錸-188-微脂體奈米核醫藥物之自發性體轉移肺癌小鼠模式療效評估 | 主持人 | 2013/01/01~2013/12/31 | 國科會 | 1009000 | |
| 2013 | c-myc訊息傳導途徑與DNA損傷修補能力對低劑量游離輻射誘發之腫瘤細胞老化與旁觀者效應的影響(1/3) | 主持人 | 2013/08/01~2016/07/31 | 國科會 | 1000000 | |
| 2013 | 探討Rho訊息傳導途徑於低氧環境抑制肥胖細胞分化的角色 | 主持人 | 2013/01/01~2013/12/31 | 振陽計畫 | 399600 | |
| 2012 | 188錸-微脂體藥物診療奈米藥物對肺癌之療效與輻射劑量評估 | 主持人 | 2012/01/01~2012/12/31 | 國科會 | 750000 | |
| 2012 | 台蒙國合計畫-p53-MDM2調控途徑之單核甘酸多樣性與蒙古族群膀胱癌風險之探討 | 個人 | 主持人 | 2012/08/01~2013/10/31 | 國科會 | 540000 |
| 2012 | 多模組分子影像探討切絲蛋白與間質金屬蛋白?之表現與活性對腫瘤轉移之影響（3/3） | 主持人 | 2012/08/01~2013/07/31 | 國科會 | 820000 | |
| 2011 | 探討切絲蛋白於老化腎臟細胞中之機制與其參與之作用 | 其他 | 主持人 | 2011/08/01~2012/12/31 | 嚴慶齡醫學研究中心 | 210000 |
| 2011 | 合併188錸-微脂體奈米藥物與細胞鬆弛素對肺癌療效之動物模式探討 | 個人 | 主持人 | 2011/01/01~2011/12/31 | 國科會 | 720000 |
| 2011 | 多模組分子影像探討切絲蛋白與間質金屬蛋白?之表現與活性對腫瘤轉移之影響（2/3） | 個人 | 主持人 | 2011/08/01~2012/07/31 | 國科會 | 820000 |
| 2011 | 低氧狀態調控細胞骨幹動力行為以抑制前脂肪細胞分化能力之探討 | 個人 | 主持人 | 2011/01/01~2011/12/31 | 台北市衛生局統籌款 | 329100 |
| 2010 | 多模組分子影像探討切絲蛋白與間質金屬蛋白?之表現與活性對腫瘤轉移之影響（1/3） | 個人 | 主持人 | 2010/08/01~2011/07/31 | 國科會 | 820000 |
| 2009 | 切絲蛋白對癌細胞的輻射敏感度及入侵轉移的效應探討(3/3) | 個人 | 主持人 | 2009/08/01~2010/07/31 | 國科會 | 1120000 |
| 2009 | p53 p53—-MDM2 調控途徑之單核酸多樣性與乳癌風險之探討 | 個人 | 主持人 | 2009/01/01~2009/12/31 | 台北市衛生局統籌款 | 343814 |
| 2008 | 切絲蛋白對癌細胞的輻射敏感度及入侵轉移的效應探討(2/3) | 個人 | 主持人 | 2008/08/01~2009/07/31 | 國科會 | 1600601 |
| 2008 | 建立多功能報導基因影像技術追蹤切絲蛋白對腫瘤生長之影響 | 個人 | 主持人 | 2008/08/01~2007/07/31 | 北榮嚴慶齡醫學研究中心 | 300000 |
| 2007 | 切絲蛋白對癌細胞的輻射敏感度及入侵轉移的效應探討(1/3) | 個人 | 主持人 | 2007/08/01~2008/07/31 | 國科會 | 1120000 |
| 2006 | 抑制肌動蛋白細胞骨架對癌細胞輻射敏感度的影響 | 個人 | 主持人 | 2006/08/01~2007/07/31 | 國科會 | 1111000 |
| 2006 | 致癌基因MDM2之單核苷酸多型性與癌症發生關聯性之研究 | 個人 | 主持人 | 2006/11/15~2007/11/14 | 台北市政府衛生局 | 601558 |
產學合作
| 年度 | 計畫名稱 | 合作廠商 | 執行期間 | 執行經費(元) |
| 2015 | 【福陞興業股份有限公司】以切絲蛋白為標的之抗老化產品開發 | 福陞興業股份有限公司 | 2015/01/01~2015/12/31 | 495000 |
校內服務
| 年度 | 服務類別 | 服務單位 | 服務職稱 |
| 107~110 | 行政主管(Administrative Directorship) | 生物醫學影像暨放射科學系 | 系主任 |
| 106~109 | 導師(mentor) | 醫放系大學部 | 導師 |
| 103~104 | 委員會(Committee) | 醫放系課程委員會 | 委員 |
| 102~ | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 導師輔導知能研討工作坊 | 研習 |
| 102~102 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 感謝 我師-教師節歡慶感恩活動 | 導師 |
| 102~102 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 導師輔導知能研討工作坊 | 導師 |
| 101~101 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級演講 (李遠哲) | 導師 |
| 101~101 | 行政主管(Administrative Directorship) | 校級演講 (陳芳明) | 導師 |
| 101~101 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 早安神農坡 | 導師 |
| 101~ | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級演講 (劉兆玄) | 導師 |
| 101~ | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級演講 (朱敬一) | 導師 |
| 101~ | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級演講 (陳義芝) | 導師 |
| 101~ | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 親師座談會 | 導師 |
| 101~ | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 早安神農坡 | 導師 |
| 101~103 | 委員會(Committee) | 生物安全委員會 | 委員 |
| 101~102 | 委員會(Committee) | 實驗動物照護及使用委員會 | 委員 |
| 101~104 | 導師(mentor) | 生物醫學影像暨放射科學系 | 導師 |
| 100~102 | 委員會(Committee) | 血液分析儀使用管理委員會 | 主任委員 |
| 99~100 | 委員會(Committee) | 學院級課程委員會 | 委員 |
| 99~101 | 委員會(Committee) | 環安委員會 | 遴選委員 |
| 99~99 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級演講 (顏鴻森) | 導師 |
| 98~98 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(劉必榮) | 出席 |
| 98~98 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(鄭愁予) | 出席 |
| 98~98 | 其他(Others) | 第六屆台灣分子生物影像學會暨台北國際分子影像學術研討會 | 活動籌備與聯繫 |
| 98~98 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 神農坡之夜 | 導師 |
| 98~98 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 第四次校級學術演講(嚴長壽總裁) | 導師 |
| 97~101 | 導師(mentor) | 生物醫學影像暨放射科學系 | 導師 |
| 97~97 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(黃鍔院士) | 導師 |
| 97~97 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(賴其萬教授) | 導師 |
| 97~97 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(李建賢院長) | 導師 |
| 97~97 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 「如何設計導師課程」研習營 | 導師 |
| 97~97 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 導師新制暨知能研討工作坊 | 導師 |
| 97~97 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 97學年度導師會議 | 導師 |
| 97~97 | 其他(Others) | 醫事放射師之教考訓用制度與國際接軌研討會 | 活動籌備與聯繫 |
| 96~97 | 委員會(Committee) | 儀器管理委員會 | 委員 |
| 96~98 | 委員會(Committee) | 動物管理委員會 | 委員 |
| 96~96 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(徐明達教授) | 導師 |
| 96~96 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(邱爾德院長) | 導師 |
| 96~96 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 校級學術演講(陳宜民教授) | 導師 |
| 96~96 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 導師新制暨知能研討工作坊 | 導師 |
| 96~96 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 導師新制說明會 | 導師 |
| 96~96 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 全校研究所師生座談會 | 導師 |
| 96~96 | 出席校內重大活動(Attendence of extracurricular activities or university Colloquium) | 全校大學部師生座談會 | 導師 |
| 95~97 | 導師(mentor) | 陽明大學生物醫學影像暨放射科學系 | 導師 |
| 95~95 | 其他(Others) | 第二屆生物醫學影像暨放射科學研討會 | 活動策劃與籌備 |
校外服務
| 年度 | 服務類別 | 服務單位 | 服務職稱 |
| 109~111 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | MDPI-Cells | 審查人(Reviewer) |
| 109~111 | 國際學術期刊(International Academic Journal)-主編(Editor-in-Chief or Editor) | MDPI – Processes | 主編(Editor-in-Chief or Editor) |
| 108~110 | 民間機構(non-governmental organization)-召集人(Convener) | 台灣分子生物影像學會 | 理監事或董事(Member of Board of Directors) |
| 108~110 | 國際學術期刊(International Academic Journal)-編輯委員(Editorial Board Member) | Spandidos Publications – Oncology Letters | 編輯委員(Editorial Board Member) |
| 107~107 | 政府部門(Governmental organization)-審查委員(Committee member) | 科技部 | 審查委員(Committee member) |
| 107~107 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Spandidos Publications – Oncology Letter | 審查人(Reviewer) |
| 107~107 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Spandidos Publications – Molecular Medicine Report | 審查人(Reviewer) |
| 107~107 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Dove Medical Press : OncoTargets and Therapy. | 審查人(Reviewer) |
| 106~107 | 民間機構(non-governmental organization)-其他(Others) | 國家衛生研究院實驗動物照護及使用委員會 | 其他(Others) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Oncotarget | 審查人(Reviewer) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Technology in cancer research & treatment (SAGE) | 審查人(Reviewer) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Spandidos Publications – International Journal of Molecular Medicine | 審查人(Reviewer) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Spandidos Publications-International Journal of Molecular Medicine | 審查人(Reviewer) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Springer- Breast Cancer Research and Treatment | 審查人(Reviewer) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | IOP – Nanotechnology | 審查人(Reviewer) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | DovePress – OncoTargets and Therapy | 審查人(Reviewer) |
| 106~106 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Spandidos Publication – International Journal of Molecular Medicine | 審查人(Reviewer) |
| 106~107 | 民間機構(non-governmental organization)-其他(Others) | 台灣中子捕獲治療研究學會舉辦之ICNCT國際會議籌備 | 其他(Others) |
| 105~108 | 國際學術期刊(International Academic Journal)-編輯委員(Editorial Board Member) | AIMS Medical Science | 編輯委員(Editorial Board Member) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Springer-Tumor Biology | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Baishideng Publishing Group Inc – World Journal of Gastroenterology | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | DOVE Press – International Journal of Nanomedicine. | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Elsvier – Chemico-Biological Interactions | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Dove Press – OncoTargets and Therapy. | 審查人(Reviewer) |
| 105~ | 國際學術期刊(International Academic Journal)-編輯委員(Editorial Board Member) | Lung Cancers- Clinics in Oncology | 編輯委員(Editorial Board Member) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | IOP Publishing | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | PLoS One | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Current gene therapy | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Journal of Biotechnology | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | International Journal of Molecular Science | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Nanotechnology | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Nanotechnology | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | PLoS One | 審查人(Reviewer) |
| 105~105 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Oncotarget | 審查人(Reviewer) |
| 104~104 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Nature Publishing Group | 審查人(Reviewer) |
| 104~104 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Baishideng publishing group | 審查人(Reviewer) |
| 104~104 | 民間機構(non-governmental organization)-其他(Others) | ARCCNM/AOFNMB | 其他(Others) 國際會議籌備委員 |
| 104~104 | 政府部門(Governmental organization)-委員 | 104學年度「衛生福利部原住民及離島地區醫事人員養成計畫」 | 口試委員 |
| 104~104 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Hindawi Publishing Corporation – BioMed Research International | 審查人(Reviewer) |
| 104~104 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Editorial Manager – Annals of Hepatology | 審查人(Reviewer) |
| 104~104 | 政府部門(Governmental organization)-審查委員(Committee member) | Grant review for Health and Medical Research Fund from The Government of the Hong Kong Special Administrative Region (HKSAR) | 審查委員(Committee member) |
| 104~104 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Springer – Tumor Biology | 審查人(Reviewer) |
| 104~104 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | DOVEPress OncoTargets and Therapy | 審查人(Reviewer) |
| 104~106 | 民間機構(non-governmental organization)-理監事或董事(Member of Board of Directors) | 臺灣中子捕獲治療研究學會 | 理監事或董事(Member of Board of Directors) |
| 103~103 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Scientific Reports | 審查人(Reviewer) |
| 103~103 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | World Journal of Hepatology | 審查人(Reviewer) |
| 103~103 | 政府部門(Governmental organization)-審查委員(Committee member) | 考選部 | 審查委員(Committee member) |
| 103~103 | 其他(Others)-其他(Others) | 華夏技術學院 | 新聘教師外審委員 |
| 103~103 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | World Journal of Neurology, Baishideng Publishing Group Inc | 審查人(Reviewer) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Springer-Molecular Imaging and Biology | 審查人(Reviewer/Referee) |
| 102~102 | 政府部門(Governmental organization)-審查委員(Committee member) | Health and Medical Research Fund of the Food and Health Bureau under The Government of the Hong Kong SAR | 審查委員(Committee member) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | International Journal of Medical Sciences | 審查人(Reviewer/Referee) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Tumor Biology | 審查人(Reviewer/Referee) |
| 102~102 | 政府部門(Governmental organization)-審查委員(Committee member) | 國家衛生研究院實驗動物照護及使用委員會 | 院外審查委員(Committee member) |
| 102~102 | 國內學術期刊(Domestic Academic Journal)-審查人(Reviewer or Referee) | Biomedical Journal | 審查人(Reviewer/Referee) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Springer-Molecular Biology Reports | 審查人(Reviewer/Referee) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Chinese Science Bulletin | 審查人(Reviewer/Referee) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | BMC Complementary and Alternative Medicine | 審查人(Reviewer/Referee) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Biomed Central/Radiation Oncology | 審查人(Reviewer/Referee) |
| 102~102 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | World Journal of Gastroenterology | 審查人(Reviewer/Referee) |
| 101~101 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | 2nd International Conference on Engineering and Technology Innovation 2012 | 審查人(Reviewer/Referee) |
| 101~101 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Dove Medical Press | 審查人(Reviewer/Referee) |
| 100~100 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Antioxidants & Redox Signaling (ARS) | 審查人(Reviewer/Referee) |
| 100~100 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Journal of Cell and Animal Biology | 審查人(Reviewer/Referee) |
| 100~100 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | The Chinese Journal of Physiology | 審查人(Reviewer/Referee) |
| 99~101 | 民間機構(non-governmental organization)-其他(Others) | 台灣分子生物影像學會 | 秘書長 |
| 99~99 | 民間機構(non-governmental organization)-其他(Others) | 天使心家族社會福利基金會 (「336愛奇兒日」嘉年華遊行&黃昏大型音樂會) | 導師 |
| 99~ | 民間機構(non-governmental organization)-其他(Others) | 台灣分子生物影像學會 | 秘書長 |
| 98~99 | 國際學術期刊(International Academic Journal)-審查人(Reviewer or Referee) | Biomedical Engineering | 審查人(Reviewer/Referee) |
| 95~99 | 民間機構(non-governmental organization)-理監事或董事(Member of Board of Directors) | 台灣分子生物影像學會 | 理事 |
邀請演講
| 時間(起) | 時間(迄) | 演講名稱 | 類別 | 邀請單位/會議 |
| 2021/10/29 | 2021/10/29 | Low dose radiation induced cellular senescence and bystander effect associated metastasis phenomenon by up-regulation of c-Myc oncogene and cofilin-1 | Invited | Solarz International Lab |
| 2018/12/19 | 2018/12/19 | Cofilin-1 stabilized actin cytoskeleton induces cellular senescence via TEAD1-p27kip1 signal pathway | Invited | 恩主公紀念醫院 |
| 2017/10/10 | 2018/1/12 | Remnant living cells in late-stage tumors exhibit cancer stem cell-like properties and their responses to various tumor treatment modalities combining the immunoadjuvant agent | Invited | 香港理工大學 醫療科技’醫療科技及資訊學系 |
| 2015/12/31 | 2015/12/31 | 放射醫學造影簡介與研究經驗分享 | Invited | 三重中央扶輪社 |
| 2014/9/12 | 2014/9/12 | Optical Molecular Imaging-Application | Invited | Taiwanese Socity of Molecular Imaging |
| 2011/9/9 | 2011/9/9 | Use of the piggyBac jumping gene system for tumor imaging | Invited | 榮總教學研究部 |
| 2010/11/12 | 2010/11/12 | Optical Imaging system in vivo & Xenogen’s IVIS® Series | Invited | 儀器科技研究中心/醫學分子影像技術研習班 |
| 2010/8/28 | 2010/8/28 | Cancer Biology and Molecular Imaging | Invited | 分子生物影像學會與核醫學會/Molecular Imaging of Cancer: From Molecules to Humans繼續教育課程 |
| 2009/12/24 | 2009/12/24 | 分子基因影像之原理與技術 | Invited | 大葉大學 |
| 2009/10/15 | 2009/10/17 | Multi-modality Imaging of the effects of actin depolymerizing factor (ADF)/cofilin on tumorigenesis using a small animal model | Invited | 14th World Congress on Advances in Oncology and 12th International Symposium on Molecular Medicine |
| 2009/9/10 | 2009/9/12 | The cell cycleand tumorigenesis inhibiton by over-expressed cofilin | Invited | 2009年分子醫學學程聯合Retreat |
| 2009/4/10 | 2009/4/10 | Involvement of p53-independent growth arrest following destabilization of actin cytoskeleton | Invited | 陽明大學 醫學技術學系 |
| 2009/3/4 | 2009/3/4 | Non-invasive Imaging of tumor suppression effect by over-expressed cofilin | Invited | 國家衛生研究院醫學工程組 |
指導研究生及碩博士論文
| 畢業否 | 年度 | 班別 | 姓名 | 論文名稱 |
| 畢業 | 93 | 博士 | 劉欣怡 | 抑制SESN2或XPC基因表現增加惡性腦瘤U87細胞之氧化性傷害 |
| 畢業 | 94 | 博士 | 孫櫻芳 | 利用磁振頻譜量測小腦代謝物暨基因體分析探討疑似底絲樂克斯亞症候群受試者之特性 |
| 畢業 | 94 | 碩士 | 劉智超 | 切絲蛋白影響細胞輻射敏感度之體內研究 |
| 畢業 | 96 | 碩士 | 李元皓 | Induction of a Senescence-like Phenomenon in H1299 Cells by Overexpression of Cofilin Is Dependent on p27kip1 |
| 畢業 | 96 | 博士 | 蔡政翰 | 切絲蛋白穩定細胞為絲骨架近而調控YAP1-p27kip1訊息傳導路徑引發細胞老化現象 |
| 畢業 | 97 | 碩士 | 江佩珣 | 探討切絲蛋白於細胞週期進行時之表現量變化與細胞放射敏感度之關聯性 |
| 畢業 | 97 | 碩士 | 蔡瀚儀 | 分析p53-MDM2調控途徑之單核苷酸多型性與台灣族群的乳癌發生率之關連性 |
| 畢業 | 98 | 碩士 | 王孝頤 | 利用piggyBac跳躍子建立多模組分子影像模式偵測活體內小鼠乳癌生長行為 |
| 畢業 | 98 | 碩士 | 周彥廷 | 探討氧化壓力誘導致癌基因c-myc 及切絲蛋白大量表現引發細胞老化之現象 |
| 畢業 | 98 | 碩士 | 黃天恆 | 切絲蛋白的表現量與活性於前脂肪細胞分化能力 |
| 畢業 | 98 | 碩士 | 邱于玟 | 第一型切絲蛋白之第三位絲氨酸殘基受磷酸化後影響放射敏感度之探討 |
| 畢業 | 99 | 博士 | 林亮廷 | |
| 畢業 | 100 | 碩士 | 陳盈伶 | 探討體內轉移癌症幹細胞的輻射抗性與上皮-間質轉化之關聯 |
| 畢業 | 100 | 碩士 | 羅佳茜 | 探討低劑量游離輻射調控致癌基因c-Myc和切絲蛋白促進細胞老化和周邊非照射細胞轉移能力之現象 |
| 畢業 | 100 | 碩士 | 蔡政良 | |
| 畢業 | 100 | 碩士 | 林詩婷 | |
| 畢業 | 102 | 碩士 | 廖曼均 | |
| 肄業 | 100 | 碩士 | 林韋宏 | |
| 肄業 | 100 | 博士 | 王柏勝 | |
| 肄業 | 102 | 博士 | 張淳湲 | |
| 肄業 | 103 | 碩士 | 王鈞右 | |
| 肄業 | 103 | 碩士 | 邱莘予 | |
| 肄業 | 103 | 碩士 | 杜元亨 |
獲獎
| 年度 | 提供單位 | 獲獎項目 | 獲獎日期 |
| 107 | Symposium of Medical Imaging and Radiological Science, SMIRS | English Oral Presentation Third Place | 107.09.29 |
| 102 | 第八屆醫學影像暨放射科學研討會 | 海報組第一名及第三名 | 2013.5.25 |
| 102 | 教育部、國科會 | 教師學術卓越獎勵 | 102.8.1至104.7.31 |
| 102 | World Molecular Imaging Congress | Poster Award | 2013.9.18-2013.9.21 |
| 101 | 第十七屆台灣癌症聯合學術年會 | 海報論文佳作 | 2012.5.5 |
| 101 | 第七屆國際醫學影像暨放射科學研討會 | 海報論文獎第一名 | 2012.5.26 |
| 100 | 教育部、國科會 | 100年度教師學術卓越獎勵 | 100年8月1日至102年7月31日 |
其他特殊研究成果
| 其他特殊研究成果 |
| Dear Dr. Lee, We are pleased to inform you that your chapter has been downloaded 2000 times to date. CHAPTER TITLE: Cytoskeletal Organization and Rb Tumor Suppressor Gene BOOK TITLE: Retinoblastoma: An Update on Clinical, Genetic Counseling, Epidemiology and Molecular Tumor Biology |
聯絡方式
辦公室： 實驗大樓 B318室
電話：(02)2826-7000 #67189(office) (02)2826-7000 #65570(lab)
電子信箱：yjlee2@nycu.edu.tw
諮詢時間：週二 10:00 ~ 12:00